Metabolite Changes Following Consumption Of Different Protein Drinks In Singapore Older Adults
NCT ID: NCT06956131
Last Updated: 2025-05-02
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
RECRUITING
NA
32 participants
INTERVENTIONAL
2025-05-29
2025-12-31
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
The Effect of Ingesting a Novel Algae Protein Source on Rested and Exercised Muscle Protein Synthesis Rates in Older Adults.
NCT06852547
Protein Nutrition for Muscle Hypertrophy in Older Adults
NCT02315391
The Bioavailability of Multiple Novel, Sustainable, Non-animal Derived Protein Sources
NCT04297137
Assessing the Appearance of Amino Acids in Circulation Following Consumption of Protein Beverages
NCT07293091
Influence of Reduced Daily Step Count and Anabolic Interventions on Muscle Protein Metabolism in Older Persons
NCT02347137
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
CROSSOVER
PREVENTION
TRIPLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Casein Protein Drink
30 g protein equivalent of casein protein isolate dissolved in \~250 mL of water
Casein Protein Isolate Drink
30 g protein equivalent of casein protein isolate dissolved in \~250 mL of water
Whey Protein Drink
30 g protein equivalent of whey protein isolate dissolved in \~250 mL of water
Whey Protein Isolate Drink
30 g protein equivalent of whey protein isolate dissolved in \~250 mL of water
Soy Protein Drink
30 g protein equivalent of soy protein isolate dissolved in \~250 mL of water
Soy Protein Isolate Drink
30 g protein equivalent of soy protein isolate dissolved in \~250 mL of water
Maltodextrin Drink
30 g carbohydrate equivalent of maltodextrin powder dissolved in \~250 mL of water
Maltodextrin Drink
30 g carbohydrate equivalent of maltodextrin powder dissolved in \~250 mL of water
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Casein Protein Isolate Drink
30 g protein equivalent of casein protein isolate dissolved in \~250 mL of water
Whey Protein Isolate Drink
30 g protein equivalent of whey protein isolate dissolved in \~250 mL of water
Soy Protein Isolate Drink
30 g protein equivalent of soy protein isolate dissolved in \~250 mL of water
Maltodextrin Drink
30 g carbohydrate equivalent of maltodextrin powder dissolved in \~250 mL of water
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Adults 60 to 80 years old (inclusive)
* (If applicable) Postmenopausal
* BMI of 18·5 to 30 kg/m2 (inclusive)
Exclusion Criteria
* Weight change \>3 kg in the past 3 months
* Exercising vigorously over the past 3 months (i.e., engaging in high-intensity exercises for more than 3 hours a week, where high-intensity exercises leave one out of breath and unable to talk or sing during the workout)
* Current smokers or have quit smoking for less than 5 years
* Drinking \>2 alcoholic drinks per day (i.e., one drink is defined as either 150 ml of wine, 340 ml of beer/cider or 45 ml of distilled spirit)
* If drinking ≤2 alcoholic drinks per day, not willing to stop consumption of alcoholic beverages two days before and on the day of the test visits (total 12 days)
* Not willing to stop consumption of caffeinated beverages 10 to 12 hours before and on the day of the test visits (total 4 days)
* Taking supplements containing omega-3, magnesium, gamma-aminobutyric acid (GABA), L-theanine, melatonin and/or 5-hydroxytryptophan for the past 3 months, and not willing to discontinue usage 3 months before and during the study duration
* Currently on a specialised diet (e.g., vegetarian, vegan, weight loss diet)
* Had serious food allergies in the past, or having intolerance, sensitivities or allergies to any of the following: milk/dairy products (e.g., casein, whey), starch/starch-derived products (e.g., rice, corn, wheat, potato), soy/soy-derived products, gluten, eggs, nuts, peanuts, fish and crustaceans.
* Disease or impairment of the kidney and/or liver
* Currently diagnosed with diabetes, sleep disorders, gastrointestinal issues (e.g., lactose intolerance, irritable bowel syndrome), gout and/or G6PD deficiency
* History of diseases known to affect the central nervous system (e.g., heart disease, stroke, migraine headaches, multiple sclerosis, Parkinson's disease, mental illnesses)
* Taking antibiotics 2 weeks prior to study participation
* Taking medication known to interfere with cognitive function and mental wellbeing (e.g., benzodiazepines, antidepressants, other central nervous agents)
* Taking anti-hypertensive or cholesterol-lowering drugs for less than 3 years unless medically declared by an official doctor to be in stable condition
* Poor peripheral venous access based on past experiences with blood drawing
60 Years
80 Years
ALL
Yes
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Bezos Earth Fund
UNKNOWN
National University of Singapore
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Jung Eun Kim
Assistant Professor
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Jung Eun Kim, Ph.D., R.D.
Role: PRINCIPAL_INVESTIGATOR
National University of Singapore, Department of Food Science and Technology
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
NUS, Department of Food Science and Technology, 1 Science Drive 3, Block S13, #03-07
Singapore, , Singapore
Countries
Review the countries where the study has at least one active or historical site.
Central Contacts
Reach out to these primary contacts for questions about participation or study logistics.
Facility Contacts
Find local site contact details for specific facilities participating in the trial.
References
Explore related publications, articles, or registry entries linked to this study.
Lanng SK, Oxfeldt M, Johansen FT, Risikesan J, Hansen M, Bertram HC. Acute changes in the metabolome following resistance exercise combined with intake of different protein sources (cricket, pea, whey). Metabolomics. 2023 Nov 24;19(12):98. doi: 10.1007/s11306-023-02064-0.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
NUS-IRB-2025-19
Identifier Type: OTHER
Identifier Source: secondary_id
S31
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.