Amino-acid Uptake After Meat Protein Intake

NCT ID: NCT03301337

Last Updated: 2022-11-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

12 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-10-04

Study Completion Date

2019-10-30

Brief Summary

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The purpose of the project is to provide evidence for the use of hydrolysed meat protein (HMP) as a protein supplement for elderly who has difficulty meeting the recommended daily protein intake.

The study will investigate how the meat protein derived amino acids (from either HMP, steak or minced meat) are absorbed and released into the blood circulation of elderly persons. Hereby, the study will explore the the anabolic potential of HMP compared with common meat products.

Detailed Description

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Conditions

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Amino Acid Metabolism

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Single-blindet randomized cross-over study
Primary Study Purpose

OTHER

Blinding Strategy

DOUBLE

Investigators Outcome Assessors
Outcome assessor and investigator will be blindet. Participants cannot be blindet, as they will consume three different meat products, that we cannot mask.

Study Groups

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Hydrolyzed meat protein

D5-phenylalanine intrinsically labelled hydrolyzed meat protein (0.6 g per kg lean body mass), which will be consumed together with a full meal.

Group Type EXPERIMENTAL

Meat protein absorption

Intervention Type DIETARY_SUPPLEMENT

Meat protein absorption when digested together with a full meal.

Minced Meat

D5-phenylalanine intrinsically labelled hydrolyzed meat protein (0.6 g per kg lean body mass), which will be consumed together with a full meal.

Group Type EXPERIMENTAL

Meat protein absorption

Intervention Type DIETARY_SUPPLEMENT

Meat protein absorption when digested together with a full meal.

Beef

D5-phenylalanine intrinsically labelled hydrolyzed meat protein (0.6 g per kg lean body mass), which will be consumed together with a full meal.

Group Type EXPERIMENTAL

Meat protein absorption

Intervention Type DIETARY_SUPPLEMENT

Meat protein absorption when digested together with a full meal.

Interventions

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Meat protein absorption

Meat protein absorption when digested together with a full meal.

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Healthy
* Untrained

Exclusion Criteria

* below 65 years of age
* BMI above 30
* Smokers
* Vegetarians
* Subjects with diabetes or other metabolic diseases
* Medical treatment affecting protein synthesis
* Gastro-intestinal problems, reduced liver or kidney function, elevated blood pressure, atherosclerosis
* More than 5 ours regular physical activity per week (except physical activity related to commuting)
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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DC Ingredients

UNKNOWN

Sponsor Role collaborator

Bispebjerg Hospital

OTHER

Sponsor Role lead

Responsible Party

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Jakob Agergaard

Postdoc, PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Jakob Agergaard, PhD

Role: PRINCIPAL_INVESTIGATOR

Institute of Sports Medicine, Copenhagen

Locations

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Institute of Sports Medicine Copenhagen

Copenhagen, , Denmark

Site Status

Countries

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Denmark

Other Identifiers

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BBH 135

Identifier Type: -

Identifier Source: org_study_id

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