Protein Ingestion and Resistance Exercise in Elderly

NCT ID: NCT01074879

Last Updated: 2010-02-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

220 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-08-31

Study Completion Date

2009-12-31

Brief Summary

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The mail goal of this randomized controlled, dietary intervention study is to investigate whether protein supplementation in combination with resistance exercise can increase muscle mass and strength in elderly. Loss of muscle mass and -strength is frequent in this group. Participants (N = 220, equal distribution between men and women) are randomized to one of three groups receiving different quantities and qualities of protein supplementation after exercise. The results of this study will be used to form recommendations regarding diet and exercise for the prevention of this frequent health problem in elderly.

Detailed Description

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Conditions

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Healthy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Whey protein

20 g whey protein + 20 g carbohydrates

Group Type EXPERIMENTAL

Whey protein

Intervention Type DIETARY_SUPPLEMENT

Dietary supplement after training

Milk protein

20 g milk protein + 20 g carbohydrates

Group Type EXPERIMENTAL

Milk protein

Intervention Type DIETARY_SUPPLEMENT

Dietary supplement after training

Carbohydrates

40 g carbohydrates

Group Type ACTIVE_COMPARATOR

Carbohydrates

Intervention Type DIETARY_SUPPLEMENT

Dietary supplement after training

Interventions

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Whey protein

Dietary supplement after training

Intervention Type DIETARY_SUPPLEMENT

Milk protein

Dietary supplement after training

Intervention Type DIETARY_SUPPLEMENT

Carbohydrates

Dietary supplement after training

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* 65 years and older

Exclusion Criteria

* uncontrolled coronary heart disease
* pharmacological interventions with drugs known to affect muscle mass
* major orthopedic disease
* low cognitive function.
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Landspitali University Hospital Research Fund

OTHER

Sponsor Role collaborator

University of Iceland

OTHER

Sponsor Role lead

Locations

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Unit for Nutrition Research

Reykjavik, , Iceland

Site Status

Countries

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Iceland

References

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Og G, M C, Pv J, I T, A R. Associations of physical activity with vitamin D status depends on obesity status in old adults. Clin Nutr ESPEN. 2020 Oct;39:222-226. doi: 10.1016/j.clnesp.2020.06.009. Epub 2020 Jul 12.

Reference Type DERIVED
PMID: 32859321 (View on PubMed)

Geirsdottir OG, Chang M, Jonsson PV, Thorsdottir I, Ramel A. Obesity, Physical Function, and Training Success in Community-Dwelling Nonsarcopenic Old Adults. J Aging Res. 2019 Feb 18;2019:5340328. doi: 10.1155/2019/5340328. eCollection 2019.

Reference Type DERIVED
PMID: 30906596 (View on PubMed)

Geirsdottir OG, Chang M, Briem K, Jonsson PV, Thorsdottir I, Ramel A. Gender, Success, and Drop-Out during a Resistance Exercise Program in Community Dwelling Old Adults. J Aging Res. 2017;2017:5841083. doi: 10.1155/2017/5841083. Epub 2017 Aug 14.

Reference Type DERIVED
PMID: 28890833 (View on PubMed)

Arnarson A, Gudny Geirsdottir O, Ramel A, Jonsson PV, Thorsdottir I. Insulin-Like Growth Factor-1 and Resistance Exercise in Community Dwelling Old Adults. J Nutr Health Aging. 2015 Oct;19(8):856-60. doi: 10.1007/s12603-015-0547-3.

Reference Type DERIVED
PMID: 26412290 (View on PubMed)

Ramel A, Geirsdottir OG, Jonsson PV, Thorsdottiri I. C-Reactive Protein and Resistance Exercise in Community Dwelling Old Adults. J Nutr Health Aging. 2015 Aug;19(7):792-6. doi: 10.1007/s12603-015-0548-2.

Reference Type DERIVED
PMID: 26193865 (View on PubMed)

Geirsdottir OG, Arnarson A, Ramel A, Briem K, Jonsson PV, Thorsdottir I. Muscular strength and physical function in elderly adults 6-18 months after a 12-week resistance exercise program. Scand J Public Health. 2015 Feb;43(1):76-82. doi: 10.1177/1403494814560842. Epub 2014 Nov 27.

Reference Type DERIVED
PMID: 25431460 (View on PubMed)

Arnarson A, Ramel A, Geirsdottir OG, Jonsson PV, Thorsdottir I. Changes in body composition and use of blood cholesterol lowering drugs predict changes in blood lipids during 12 weeks of resistance exercise training in old adults. Aging Clin Exp Res. 2014 Jun;26(3):287-92. doi: 10.1007/s40520-013-0172-0. Epub 2013 Dec 1.

Reference Type DERIVED
PMID: 24293371 (View on PubMed)

Geirsdottir OG, Arnarson A, Ramel A, Jonsson PV, Thorsdottir I. Dietary protein intake is associated with lean body mass in community-dwelling older adults. Nutr Res. 2013 Aug;33(8):608-12. doi: 10.1016/j.nutres.2013.05.014. Epub 2013 Jun 27.

Reference Type DERIVED
PMID: 23890349 (View on PubMed)

Arnarson A, Gudny Geirsdottir O, Ramel A, Briem K, Jonsson PV, Thorsdottir I. Effects of whey proteins and carbohydrates on the efficacy of resistance training in elderly people: double blind, randomised controlled trial. Eur J Clin Nutr. 2013 Aug;67(8):821-6. doi: 10.1038/ejcn.2013.40. Epub 2013 Mar 13.

Reference Type DERIVED
PMID: 23486511 (View on PubMed)

Ramel A, Arnarson A, Geirsdottir OG, Jonsson PV, Thorsdottir I. Glomerular filtration rate after a 12-wk resistance exercise program with post-exercise protein ingestion in community dwelling elderly. Nutrition. 2013 May;29(5):719-23. doi: 10.1016/j.nut.2012.10.002. Epub 2013 Jan 11.

Reference Type DERIVED
PMID: 23317926 (View on PubMed)

Geirsdottir OG, Arnarson A, Briem K, Ramel A, Jonsson PV, Thorsdottir I. Effect of 12-week resistance exercise program on body composition, muscle strength, physical function, and glucose metabolism in healthy, insulin-resistant, and diabetic elderly Icelanders. J Gerontol A Biol Sci Med Sci. 2012 Nov;67(11):1259-65. doi: 10.1093/gerona/gls096. Epub 2012 Apr 10.

Reference Type DERIVED
PMID: 22496538 (View on PubMed)

Geirsdottir OG, Arnarson A, Briem K, Ramel A, Tomasson K, Jonsson PV, Thorsdottir I. Physical function predicts improvement in quality of life in elderly Icelanders after 12 weeks of resistance exercise. J Nutr Health Aging. 2012 Jan;16(1):62-6. doi: 10.1007/s12603-011-0076-7.

Reference Type DERIVED
PMID: 22238003 (View on PubMed)

Other Identifiers

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071323007

Identifier Type: -

Identifier Source: org_study_id

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