Speed of Glucose Absorption During Exercise

NCT ID: NCT06768333

Last Updated: 2025-03-06

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 10 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2025-01-06
• Study Completion Date: 2025-02-05

Brief Summary

The purpose of this study is to look at how fast commercially available supplements containing carbohydrates can get into the bloodstream during repeated sprint cycles. This will build from a pervious study where the investigators tested these supplements on healthy participants during a resting oral glucose tolerance trial. The investigators will be testing three supplements, namely Voom Pocket Rocket, SIS Go Isotonic Energy Gel, and Maurten Gel 160. Each participant will complete all three conditions, consuming one of each supplement at random per condition. The study requires participation from male and female runners, cyclists and triathletes who are aged between 18-40.

Each visit will take approximately 1 hour, and three experimental visits per participant. The study will involve frequent blood sampling and the continuous monitoring of gas exchange (oxygen/carbon dioxide). Blood sampling via cannulation will be used to analyse the lactate, glucose, and electrolyte content of the blood. Gas exchange will measure the oxygen breathed in and carbon dioxide breathed out throughout the exercise.

The investigators plan to carry out the study on 10 participants who will be a mix of male and female runners, cyclists and triathletes.

Conditions

Healthy Nutrition; Healthy

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: CROSSOVER
• Primary Study Purpose: BASIC_SCIENCE
• Blinding Strategy: DOUBLE

Study Groups

Voom Pocket Rocket Electro Energy Bar

After at least 48 hours, every participant will undergo a different condition

Group Type: EXPERIMENTAL

45 grams Voom Pocket Rocket Electro Energy

Intervention Type: DIETARY_SUPPLEMENT

Participants will be required to consume 45 grams (in carbohydrates) of the Voom Pocket Rocket Electro Energy on one of the three experimental visits. Participants will have blood glucose, blood lactate, and electrolytes sampled throughout five 15-second repeated cycling intervals interspersed with 3 minutes active recovery. Gas exchange will also be monitored throughout the 1-hour study visit.

Maurten Gel 160

After at least 48 hours, every participant will undergo a different condition

Group Type: EXPERIMENTAL

45 grams Maurten Gel 160

Intervention Type: DIETARY_SUPPLEMENT

Participants will be required to consume 45 grams (in carbohydrates) of the Maurten Gel 160 on one of the three experimental visits. Participants will have blood glucose, blood lactate, and electrolytes sampled throughout five 15-second repeated cycling intervals interspersed with 3 minutes active recovery. Gas exchange will also be monitored throughout the 1-hour study visit.

SIS Go Isotonic Energy Gel

After at least 48 hours, every participant will undergo a different condition

Group Type: EXPERIMENTAL

45 grams SIS Go Isotonic Energy Gel

Intervention Type: DIETARY_SUPPLEMENT

Participants will be required to consume 45 grams (in carbohydrates) of the SIS Go Isotonic Energy Gel on one of the three experimental visits. Participants will have blood glucose, blood lactate, and electrolytes sampled throughout five 15-second repeated cycling intervals interspersed with 3 minutes active recovery. Gas exchange will also be monitored throughout the 1-hour study visit.

Interventions

45 grams Voom Pocket Rocket Electro Energy

Participants will be required to consume 45 grams (in carbohydrates) of the Voom Pocket Rocket Electro Energy on one of the three experimental visits. Participants will have blood glucose, blood lactate, and electrolytes sampled throughout five 15-second repeated cycling intervals interspersed with 3 minutes active recovery. Gas exchange will also be monitored throughout the 1-hour study visit.

Intervention Type: DIETARY_SUPPLEMENT

45 grams Maurten Gel 160

Participants will be required to consume 45 grams (in carbohydrates) of the Maurten Gel 160 on one of the three experimental visits. Participants will have blood glucose, blood lactate, and electrolytes sampled throughout five 15-second repeated cycling intervals interspersed with 3 minutes active recovery. Gas exchange will also be monitored throughout the 1-hour study visit.

Intervention Type: DIETARY_SUPPLEMENT

45 grams SIS Go Isotonic Energy Gel

Participants will be required to consume 45 grams (in carbohydrates) of the SIS Go Isotonic Energy Gel on one of the three experimental visits. Participants will have blood glucose, blood lactate, and electrolytes sampled throughout five 15-second repeated cycling intervals interspersed with 3 minutes active recovery. Gas exchange will also be monitored throughout the 1-hour study visit.

Intervention Type: DIETARY_SUPPLEMENT

Eligibility Criteria

Inclusion Criteria

• Aged between 18-40 years
• Male or female
• Tier 2 athletes - local level representation, training ~ 3 times per week, training with a purpose to compete, identify with a specific sport, limited skill development (McKay et al., 2021)

Exclusion Criteria

• Allergies to any listed ingredients on any supplements.
• Diabetes (type 1 or 2)
• Any medical conditions
• Smokers
• Any injury that would prevent them from exercising
• Anyone using drugs or medication (not including contraception)
• Anyone consuming alcohol within 24 hours of the study
• Exercise must be restricted within 24 hours of the study
• Caffeine must not be consumed within 24 hours of testing as it can significantly enhance carbohydrate oxidation rates (Yeo et al., 2005)
• Diets including high-carbohydrate-low-fat (HCLF), low-carbohydrate-high-fat (LCHF), ketogenic, and/or glycogen manipulation diets (Rauch et al., 2022)

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 40 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Lancaster University

OTHER

Sponsor Role: lead

Responsible Party

Dr. Chris Gaffney

Principal Investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Lancaster University

Lancaster, Lancashire, United Kingdom

Countries

United Kingdom

References

Rauch CE, McCubbin AJ, Gaskell SK, Costa RJS. Feeding Tolerance, Glucose Availability, and Whole-Body Total Carbohydrate and Fat Oxidation in Male Endurance and Ultra-Endurance Runners in Response to Prolonged Exercise, Consuming a Habitual Mixed Macronutrient Diet and Carbohydrate Feeding During Exercise. Front Physiol. 2022 Jan 4;12:773054. doi: 10.3389/fphys.2021.773054. eCollection 2021.

Reference Type: BACKGROUND

PMID: 35058795 (View on PubMed)

Other Identifiers

LMS-24-Dean-2

Identifier Type: -

Identifier Source: org_study_id