A Low-osmolaric Glucose Polymer Drink for Gastric Distress and Running Performance
NCT ID: NCT02401152
Last Updated: 2015-12-15
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
43 participants
INTERVENTIONAL
2015-02-28
2015-09-30
Brief Summary
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The study will consist of 3 parts. Firstly, a randomized cross-over design is used for the short distance run and the effects on GD and RP. Secondly, a parallel design is used to study the effects of the drinks on GD and RP during a longer distance run. Thirdly, the gastric emptying tests will be performed in a randomized cross-over design. Participants will be asked to fill in questionnaire on the gastric distress they experience. 40 participants will be enrolled to participate in part 1 and part 2. 10 out of 40 will participate in part 3 of the study.
Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
TRIPLE
Study Groups
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Placebo group
Sports drink containing maltodextrin
Placebo
iso-caloric sports drink with maltodextrin as CHO source
Sports drink 1
Sports drink with a specific source of carbohydrates (CHO).
Sports drink 1
Sports drink with a specific source of CHO.
Sports drink 2
Sports drink with a specific source of CHO.
Sports drink 2
Sports drink with a specific source of CHO
Interventions
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Sports drink 1
Sports drink with a specific source of CHO.
Sports drink 2
Sports drink with a specific source of CHO
Placebo
iso-caloric sports drink with maltodextrin as CHO source
Eligibility Criteria
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Inclusion Criteria
* A BMI between 18.5 and 25 kg\*m-2
* Intermediate level runners with at least 1 year of running experience, performing moderate to intensive running exercise consistently (two or more times per week for a minimum of 30 minutes each time)
Exclusion Criteria
* Having diseases, such as diabetes, kidney, liver, lung, or bowel disease, cardiovascular disease, or mental illness
* Abuse of alcohol (\>20 alcoholic consumptions per week)
* Use of medication and/or drugs
* Smoking/having smoked in the last six months
* Participating in any scientific intervention providing a treatment potentially interfering with this study's treatment (to be decided by the researchers)
* Allergic to one of the components present in the drinks, including milk (incl. lactose), soy and gluten
18 Years
35 Years
ALL
Yes
Sponsors
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Avebe U.A.
UNKNOWN
InnoSportNL
OTHER
Responsible Party
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Jeroen Wouters
Dr. Ir.
Principal Investigators
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Jeroen Wouters, Dr. Ir.
Role: PRINCIPAL_INVESTIGATOR
Locations
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InnoSportlab Papendal
Arnhem, Gelderland, Netherlands
Countries
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References
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Leiper JB, Aulin KP, Soderlund K. Improved gastric emptying rate in humans of a unique glucose polymer with gel-forming properties. Scand J Gastroenterol. 2000 Nov;35(11):1143-9. doi: 10.1080/003655200750056600.
Takii H, Takii Nagao Y, Kometani T, Nishimura T, Nakae T, Kuriki T, Fushiki T. Fluids containing a highly branched cyclic dextrin influence the gastric emptying rate. Int J Sports Med. 2005 May;26(4):314-9. doi: 10.1055/s-2004-820999.
Stephens FB, Roig M, Armstrong G, Greenhaff PL. Post-exercise ingestion of a unique, high molecular weight glucose polymer solution improves performance during a subsequent bout of cycling exercise. J Sports Sci. 2008 Jan 15;26(2):149-54. doi: 10.1080/02640410701361548.
Rehrer NJ, Brouns F, Beckers EJ, ten Hoor F, Saris WH. Gastric emptying with repeated drinking during running and bicycling. Int J Sports Med. 1990 Jun;11(3):238-43. doi: 10.1055/s-2007-1024799.
Moses FM. The effect of exercise on the gastrointestinal tract. Sports Med. 1990 Mar;9(3):159-72. doi: 10.2165/00007256-199009030-00004.
de Oliveira EP, Burini RC. Food-dependent, exercise-induced gastrointestinal distress. J Int Soc Sports Nutr. 2011 Sep 28;8:12. doi: 10.1186/1550-2783-8-12.
Ploutz-Snyder L, Foley J, Ploutz-Snyder R, Kanaley J, Sagendorf K, Meyer R. Gastric gas and fluid emptying assessed by magnetic resonance imaging. Eur J Appl Physiol Occup Physiol. 1999 Feb;79(3):212-20. doi: 10.1007/s004210050498.
Rodriguez NR, DiMarco NM, Langley S; American Dietetic Association; Dietitians of Canada; American College of Sports Medicine: Nutrition and Athletic Performance. Position of the American Dietetic Association, Dietitians of Canada, and the American College of Sports Medicine: Nutrition and athletic performance. J Am Diet Assoc. 2009 Mar;109(3):509-27. doi: 10.1016/j.jada.2009.01.005.
American Dietetic Association; Dietitians of Canada; American College of Sports Medicine; Rodriguez NR, Di Marco NM, Langley S. American College of Sports Medicine position stand. Nutrition and athletic performance. Med Sci Sports Exerc. 2009 Mar;41(3):709-31. doi: 10.1249/MSS.0b013e31890eb86.
Murray R, Bartoli W, Stofan J, Horn M, Eddy D. A comparison of the gastric emptying characteristics of selected sports drinks. Int J Sport Nutr. 1999 Sep;9(3):263-74. doi: 10.1123/ijsn.9.3.263.
Maughan RJ, Leiper JB. Limitations to fluid replacement during exercise. Can J Appl Physiol. 1999 Apr;24(2):173-87. doi: 10.1139/h99-015.
Rowlands DS, Wallis GA, Shaw C, Jentjens RL, Jeukendrup AE. Glucose polymer molecular weight does not affect exogenous carbohydrate oxidation. Med Sci Sports Exerc. 2005 Sep;37(9):1510-6. doi: 10.1249/01.mss.0000177586.68399.f5.
Zhu Y, Hsu WH, Hollis JH. The impact of food viscosity on eating rate, subjective appetite, glycemic response and gastric emptying rate. PLoS One. 2013 Jun 20;8(6):e67482. doi: 10.1371/journal.pone.0067482. Print 2013.
Siegel JA, Krevsky B, Maurer AH, Charkes ND, Fisher RS, Malmud LS. Scintigraphic evaluation of gastric emptying: are radiolabeled solids necessary? Clin Nucl Med. 1989 Jan;14(1):40-6. doi: 10.1097/00003072-198901000-00011.
Chang TM, Passaro E Jr, Shain LR, Chen WL. Physical properties of starch meals in vivo and in vitro and their influence on gastric emptying and oral glucose tolerance test. Nutrition. 1991 Nov-Dec;7(6):410-6.
Mourot J, Thouvenot P, Couet C, Antoine JM, Krobicka A, Debry G. Relationship between the rate of gastric emptying and glucose and insulin responses to starchy foods in young healthy adults. Am J Clin Nutr. 1988 Oct;48(4):1035-40. doi: 10.1093/ajcn/48.4.1035.
Other Identifiers
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LOGP-001
Identifier Type: -
Identifier Source: org_study_id