The Effects of Acute Chicory Coffee Consumption on Exercise Performance and Metabolism
NCT ID: NCT07094191
Last Updated: 2025-07-30
Study Results
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Basic Information
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COMPLETED
NA
22 participants
INTERVENTIONAL
2024-01-01
2025-06-16
Brief Summary
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Does chicory coffee influence glucose, lipid, and energy metabolism after exercise?
Does chicory coffee affect physical performance and perceived fatigue levels?
Researchers will compare chicory coffee (CC), arabica coffee (AC), and a no-drink control to see if chicory coffee has similar or unique metabolic and performance effects compared to caffeinated coffee or no intervention.
Participants will:
Consume one of the test beverages (chicory coffee, arabica coffee, or no drink) 45 minutes before performing a shuttle-run test
Complete a standardized shuttle-run exercise test
Undergo blood sample collection before and after exercise to assess glucose, lactate, LPL, TNF-α, adiponectin, and IL-6
Rate their perceived exertion and record symptoms
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Detailed Description
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Chicory coffee (CC)
Arabica coffee (AC)
Control (no beverage)
Before each trial, baseline data-including health status, dietary habits, and body composition-were collected. Participants consumed the assigned beverage 45 minutes before performing a shuttle-run test designed to assess endurance and physical performance. A 3-day washout period separated each intervention session to eliminate carryover effects.
During each session, pre- and post-exercise measurements included:
Blood glucose, lactate, blood pressure, and oxygen saturation
Subjective fatigue assessed by the Borg Rating of Perceived Exertion (RPE)
Additionally, venous blood samples were collected after exercise and analyzed for key metabolic and inflammatory biomarkers:
Lipoprotein lipase (LPL)
Tumor necrosis factor-alpha (TNF-α)
Adiponectin
Interleukin-6 (IL-6)
All blood samples were processed under cold-chain conditions and analyzed using ELISA methods. Dietary intake was monitored, and participants were instructed to maintain their usual eating habits while avoiding other caffeinated beverages during the study period.
Statistical analysis included MANOVA and ANOVA, with Bonferroni corrections used for multiple comparisons.
Conditions
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Study Design
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RANDOMIZED
CROSSOVER
OTHER
SINGLE
Study Groups
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Chicory Coffee Arm
Participants in this arm consumed a standardized dose of chicory coffee (180 mL), a caffeine-free beverage rich in polyphenols and inulin, 45 minutes prior to the shuttle-run test. This arm was designed to assess the effects of chicory coffee on metabolism, inflammation, and exercise performance.
Chicory Coffee (Caffeine-free, polyphenol-rich beverage from roasted chicory root)
A single oral dose of 180 mL chicory coffee prepared by steeping 20 grams of roasted and ground chicory root in hot water (approximately 90°C) for 5 minutes. The beverage was administered once, exactly 45 minutes before exercise, as part of a single session within a randomized crossover design. Chicory coffee is naturally caffeine-free, and rich in inulin and polyphenols, which are standardized in each preparation. No additional ingredients (milk, sugar, or flavoring) were added.
Blood lactate, glucose, blood pressure, and oxygen saturation (SpO₂) levels were measured both before and after the exercise. In addition, venous blood samples were collected post-exercise to assess serum levels of adiponectin, interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α) and LPL.
Arabica Coffee Arm
Participants in this arm consumed a standardized dose of arabica coffee (180 mL), a regular caffeinated coffee, 45 minutes prior to the shuttle-run test. This arm served as a comparison to evaluate how caffeine-containing coffee influences metabolic and performance-related parameters.
arabica coffee
A single oral dose of 180 mL Arabica coffee prepared by steeping 20 grams of roasted and ground chicory root in hot water (approximately 90°C) for 5 minutes. The beverage was administered once, exactly 45 minutes before exercise, as part of a single session within a randomized crossover design. Chicory coffee is naturally caffeine-free, and rich in inulin and polyphenols, which are standardized in each preparation. No additional ingredients (milk, sugar, or flavoring) were added. Blood lactate, glucose, blood pressure, and oxygen saturation (SpO₂) levels were measured both before and after the exercise. In addition, venous blood samples were collected post-exercise to assess serum levels of adiponectin, interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α) and LPL.
Control Arm
CONTROL ARM
no beverage control
Participants underwent the shuttle run exercise protocol in a fasted state, without consuming any food or beverages prior to the test. Blood lactate, glucose, blood pressure, and oxygen saturation (SpO₂) levels were measured both before and after the exercise. In addition, venous blood samples were collected post-exercise to assess serum levels of adiponectin, interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α) and LPL.
Interventions
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Chicory Coffee (Caffeine-free, polyphenol-rich beverage from roasted chicory root)
A single oral dose of 180 mL chicory coffee prepared by steeping 20 grams of roasted and ground chicory root in hot water (approximately 90°C) for 5 minutes. The beverage was administered once, exactly 45 minutes before exercise, as part of a single session within a randomized crossover design. Chicory coffee is naturally caffeine-free, and rich in inulin and polyphenols, which are standardized in each preparation. No additional ingredients (milk, sugar, or flavoring) were added.
Blood lactate, glucose, blood pressure, and oxygen saturation (SpO₂) levels were measured both before and after the exercise. In addition, venous blood samples were collected post-exercise to assess serum levels of adiponectin, interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α) and LPL.
arabica coffee
A single oral dose of 180 mL Arabica coffee prepared by steeping 20 grams of roasted and ground chicory root in hot water (approximately 90°C) for 5 minutes. The beverage was administered once, exactly 45 minutes before exercise, as part of a single session within a randomized crossover design. Chicory coffee is naturally caffeine-free, and rich in inulin and polyphenols, which are standardized in each preparation. No additional ingredients (milk, sugar, or flavoring) were added. Blood lactate, glucose, blood pressure, and oxygen saturation (SpO₂) levels were measured both before and after the exercise. In addition, venous blood samples were collected post-exercise to assess serum levels of adiponectin, interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α) and LPL.
no beverage control
Participants underwent the shuttle run exercise protocol in a fasted state, without consuming any food or beverages prior to the test. Blood lactate, glucose, blood pressure, and oxygen saturation (SpO₂) levels were measured both before and after the exercise. In addition, venous blood samples were collected post-exercise to assess serum levels of adiponectin, interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α) and LPL.
Eligibility Criteria
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Inclusion Criteria
Healthy status based on self-report and screening (no diagnosed chronic disease)
Moderately physically active (minimum 3 days/week of physical activity)
No regular use of medication or dietary supplements
Non-smoker
No caffeine consumption for at least 7 days prior to and during the study
Willing and able to provide informed consent
Able to complete the shuttle-run test as instructed
Exclusion Criteria
Regular caffeine use or caffeine withdrawal symptoms
Use of alcohol, stimulants, or performance-enhancing substances during the study
Known allergy or intolerance to chicory or coffee
Participation in another clinical study within the last 30 days
Any musculoskeletal or respiratory condition that prevents safe participation in exercise
Inability to comply with the dietary or testing protocol
18 Years
25 Years
MALE
Yes
Sponsors
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Fatma Özsel Özcan
OTHER
Responsible Party
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Fatma Özsel Özcan
Assistant Professor
Locations
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Halic University
Istanbul, , Turkey (Türkiye)
Countries
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References
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Saunders TJ, Palombella A, McGuire KA, Janiszewski PM, Despres JP, Ross R. Acute exercise increases adiponectin levels in abdominally obese men. J Nutr Metab. 2012;2012:148729. doi: 10.1155/2012/148729. Epub 2012 May 30.
Yamashita K, Yatsuya H, Muramatsu T, Toyoshima H, Murohara T, Tamakoshi K. Association of coffee consumption with serum adiponectin, leptin, inflammation and metabolic markers in Japanese workers: a cross-sectional study. Nutr Diabetes. 2012 Apr 2;2(4):e33. doi: 10.1038/nutd.2012.6.
Diaz-Lara FJ, Del Coso J, Garcia JM, Portillo LJ, Areces F, Abian-Vicen J. Caffeine improves muscular performance in elite Brazilian Jiu-jitsu athletes. Eur J Sport Sci. 2016 Nov;16(8):1079-86. doi: 10.1080/17461391.2016.1143036. Epub 2016 Feb 10.
Bonnema AL, Kolberg LW, Thomas W, Slavin JL. Gastrointestinal tolerance of chicory inulin products. J Am Diet Assoc. 2010 Jun;110(6):865-8. doi: 10.1016/j.jada.2010.03.025.
Other Identifiers
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2015-KAEK-79-23-03
Identifier Type: -
Identifier Source: org_study_id
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