Effect of Lyophilized Cornelian Cherry on Anaerobic Performance in Young Football Players

NCT ID: NCT07114341

Last Updated: 2025-09-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-04-01

Study Completion Date

2025-04-30

Brief Summary

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The goal of this clinical trial is to learn if a lyophilized Cornelian Cherry supplement works to improve anaerobic performance and reduce fatigue in young football players (U14-U19 age group).

The main questions it aims to answer are:

* Does taking a lyophilized Cornelian Cherry supplement improve participants' anaerobic performance as measured by the Running-based Anaerobic Sprint Test (RAST)?
* Does the supplement reduce participants' levels of fatigue after strenuous exercise?

Researchers will measure participants' performance and fatigue levels before the study begins and compare them to the levels measured after 1 week of taking the cranberry supplement. This will help determine the effect of the supplement.

Participants will:

* Take 30 grams of lyophilized Cornelian Cherry powder every day for 1 week.
* Visit the study center at the beginning and at the end of the 1-week period for checkups and tests.
* Undergo anthropometric measurements (such as height, weight, and body composition) at the start of the study.
* Perform a Running-based Anaerobic Sprint Test (RAST) and a fatigue test at the start and end of the study.

Detailed Description

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A balanced diet plays a role in preventing injuries, improving athletic performance, and accelerating post-exercise recovery in adolescents who engage in physical activity. The physiological response to exercise can vary depending on the duration, intensity, and frequency of exercise, as well as environmental conditions. Excessive reactive oxygen species (ROS) production triggered by high-intensity exercise or other stress factors in athletes can lead to oxidative stress and subsequent tissue damage by weakening the antioxidant defense system. Therefore, athletes may need to maintain increased ROS scavenging activity. Additionally, physical exercise can lead to injuries in skeletal muscle tissue, leading to decreased performance. Therefore, strategies to manage exercise-related injuries and post-exercise inflammatory processes may contribute to accelerating exercise adaptation and recovery. Recently, there has been increasing support for the possibility of improving exercise performance through supplementation with fruit-derived polyphenols. Polyphenols are secondary metabolites abundant in plant foods and are divided into four main groups: lignans, stilbenes, and flavonoids. Anthocyanins, a subclass of flavonoids, are found in red, purple, and blue vegetables and fruits. Anthocyanins are known for their antioxidant and anti-inflammatory properties, and therefore, they are thought to prevent adverse physiological effects such as fatigue and post-exercise inflammation, which can potentially occur during exercise. The potential mechanism of action is thought to be related to antioxidant and vascular effects. Turkey is among the countries where cornelian cherries, another fruit with high biological value due to their anthocyanin and other phenolic compounds, are cultivated. Randomized controlled trials have examined the effectiveness of freeze-dried cornelian cherry supplements in various disease groups. Studies have observed positive effects on lipid profiles, as well as parameters related to body mass index (BMI), body weight, waist and hip circumference, and insulin resistance. Another randomized controlled trial has indicated that cornelian cherry supplementation may be effective in accelerating post-exercise recovery in athletes. While the literature has evaluated the effects of various forms of supplementation with fruits high in anthocyanins on sports performance, studies examining anaerobic power and capacity with cornelian cherry supplementation in adolescent athletes are limited. Therefore, the purpose of this study was to evaluate the effects of freeze-dried cornelian cherry fruit on anaerobic performance in adolescent soccer players.

Conditions

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Sport Nutrition Sports Performance in Children Ergogenic Athletic Performance Ergogenic Support Sports Nutritional Sciences

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

This study designed as an intervention study.
Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Not suitable for masking.

Study Groups

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Baseline

In order to determine the standard performance of the adolescent football players in the first stage before the intervention, a Running-Based Anaerobic Sprint Test (RAST) was applied to the adolescent football players on a grass field in an open-air environment after a 10-minute warm-up exercise.

Group Type NO_INTERVENTION

No interventions assigned to this group

Cranberry Intervention

In the second phase of the study, adolescent soccer players were given 30 grams of freeze-dried cranberries containing 1187 mg/100 g anthocyanins daily for 1 week. To determine post-intervention performance, the adolescent soccer players underwent a 10-minute warm-up exercise followed by a Running-Based Anaerobic Sprint Test (RAST) on a grass field in an outdoor environment.

Group Type ACTIVE_COMPARATOR

Cranberry Intervention

Intervention Type OTHER

30 grams of lyophilized cranberry containing 1187 mg/100 g anthocyanins were given for 7 days.

Interventions

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Cranberry Intervention

30 grams of lyophilized cranberry containing 1187 mg/100 g anthocyanins were given for 7 days.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* 13-18 ages of adolescent football

Exclusion Criteria

* Disease diagnosis or history,
* Regular medication use,
* Regular nutritional supplement use,
* Being under 14 years of age,
* Being over 19 years of age.
Minimum Eligible Age

14 Years

Maximum Eligible Age

19 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Istanbul Bilgi University

OTHER

Sponsor Role lead

Responsible Party

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Hande Seven Avuk

Assistant Professor, Head of Nutrition and Dietetic Department

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Istanbul Bilgi University

Istanbul, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Reference Type BACKGROUND
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Jastrzebska AD. Comparison of usefulness of two tests measuring anaerobic performance of untrained and soccer-training girls U12. Sci Rep. 2023 Nov 9;13(1):19498. doi: 10.1038/s41598-023-46825-2.

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PMID: 30927747 (View on PubMed)

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Khoo HE, Azlan A, Tang ST, Lim SM. Anthocyanidins and anthocyanins: colored pigments as food, pharmaceutical ingredients, and the potential health benefits. Food Nutr Res. 2017 Aug 13;61(1):1361779. doi: 10.1080/16546628.2017.1361779. eCollection 2017.

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Reference Type BACKGROUND
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Volpe-Fix AR, de Franca E, Silvestre JC, Thomatieli-Santos RV. The Use of Some Polyphenols in the Modulation of Muscle Damage and Inflammation Induced by Physical Exercise: A Review. Foods. 2023 Feb 21;12(5):916. doi: 10.3390/foods12050916.

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Sawada Y, Ichikawa H, Ebine N, Minamiyama Y, Alharbi AAD, Iwamoto N, Fukuoka Y. Effects of High-Intensity Anaerobic Exercise on the Scavenging Activity of Various Reactive Oxygen Species and Free Radicals in Athletes. Nutrients. 2023 Jan 1;15(1):222. doi: 10.3390/nu15010222.

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Capra ME, Stanyevic B, Giudice A, Monopoli D, Decarolis NM, Esposito S, Biasucci G. Nutrition for Children and Adolescents Who Practice Sport: A Narrative Review. Nutrients. 2024 Aug 22;16(16):2803. doi: 10.3390/nu16162803.

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Reference Type BACKGROUND
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Other Identifiers

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CORNELIANCHERRYFOOTBALLSTUDY

Identifier Type: -

Identifier Source: org_study_id

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