Caffeine Mouth Rinsing at Different Doses in Female Team-Sport Athletes: A Randomized, Double-Blind, Placebo-Controlled Trial
NCT ID: NCT07129863
Last Updated: 2025-08-19
Study Results
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Basic Information
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COMPLETED
NA
13 participants
INTERVENTIONAL
2023-09-24
2024-12-22
Brief Summary
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To evaluate the effects of different caffeine mouth rinse concentrations (1%, 2%, and 3%) on Running Anaerobic Sprint Test (RAST) performance in female team-sport athletes.
Main Questions:
1. Do caffeine mouth rinses improve RAST performance in female team-sport athletes?
2. Do different caffeine mouth rinse concentrations affect ratings of perceived exertion (RPE)?
Method:
Thirteen trained female football and handball players (23.0 ± 4.5 years) completed four randomized, double-blind, crossover conditions (1%, 2%, and 3% caffeine mouth rinses, and placebo). Each trial involved six 35 m sprints separated by 10 s of rest. RPE was recorded immediately after each session.
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Detailed Description
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To evaluate the acute effects of different caffeine mouth rinse concentrations (1%, 2%, and 3%) on anaerobic sprint performance and perceived exertion in trained female team-sport athletes. The study sought to determine whether this non-ingestive ergogenic strategy could enhance high-intensity running performance and reduce effort perception.
Main Questions:
1. Do different caffeine mouth rinse concentrations improve Running Anaerobic Sprint Test (RAST) performance in trained female team-sport athletes?
2. Do caffeine mouth rinses at varying concentrations influence ratings of perceived exertion (RPE) compared with placebo?
Is there an optimal caffeine concentration that balances potential performance benefits with reduced perceived exertion?
Method:
Thirteen trained female athletes (mean age 23.0 ± 4.5 years) competing in football and handball participated in a randomized, double-blind, placebo-controlled, crossover trial. Each athlete completed four experimental conditions: placebo, 1% caffeine mouth rinse, 2% caffeine mouth rinse, and 3% caffeine mouth rinse. In each session, participants performed a Running Anaerobic Sprint Test (RAST) consisting of six maximal 35 m sprints separated by 10 seconds of passive recovery. The RPE was assessed immediately after each test using a 1-10 scale.
Conditions
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Study Design
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RANDOMIZED
CROSSOVER
TREATMENT
TRIPLE
Study Groups
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Placebo (water)
Placebo: Mouth rinse with plain water, containing no caffeine, serving as the control condition.
Placebo: Mouth rinse with plain water
Placebo: Mouth rinse with plain water, containing no caffeine, serving as the control condition.
Low mouth rinse caffeine concentration
Low caffeine concentration: Mouth rinse containing 1% caffeine solution (based on weight/volume).
Experimental: Low mouth rinse caffeine concentration (1%)
Arm Description: Low caffeine concentration: Mouth rinse containing 1% caffeine solution (based on weight/volume).
Moderate mouth rinse caffeine concentration
Moderate caffeine concentration: Mouth rinse containing 2% caffeine solution (based on weight/volume).
Moderate caffeine concentration (2% caffeine solution weight/volume).
Moderate caffeine concentration: Mouth rinse containing 2% caffeine solution (weight/volume).
High mouth rinse caffeine concentration
Moderate caffeine concentration: Mouth rinse containing 3% caffeine solution (based on weight/volume).
High caffeine concentration (3% caffeine solution weight/volume).
High caffeine concentration: Mouth rinse containing 3% caffeine solution (weight/volume).
Interventions
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Placebo: Mouth rinse with plain water
Placebo: Mouth rinse with plain water, containing no caffeine, serving as the control condition.
Experimental: Low mouth rinse caffeine concentration (1%)
Arm Description: Low caffeine concentration: Mouth rinse containing 1% caffeine solution (based on weight/volume).
Moderate caffeine concentration (2% caffeine solution weight/volume).
Moderate caffeine concentration: Mouth rinse containing 2% caffeine solution (weight/volume).
High caffeine concentration (3% caffeine solution weight/volume).
High caffeine concentration: Mouth rinse containing 3% caffeine solution (weight/volume).
Eligibility Criteria
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Inclusion Criteria
* Currently engaged in team sports.
* Non-smoker.
Exclusion Criteria
* Presence of a musculoskeletal injury within the six months prior to the study.
* Current smoker.
* Use of nutritional supplements or ergogenic aids that could influence sprint running performance (e.g., beta-alanine, creatine).
* Use of oral contraceptives.
* Known allergy to caffeine.
* Failure to meet the training requirement of at least six hours of team-based practice, a minimum of three days per week, over the past year.
18 Years
35 Years
FEMALE
Yes
Sponsors
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Eastern Mediterranean University
OTHER
Northumbria University
OTHER
Universidad Francisco de Vitoria
OTHER
Ankara University
OTHER
Universidad Pontificia Comillas
OTHER
Responsible Party
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Locations
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Eastern Mediterranean University
Mersin, SBF C 116, Turkey (Türkiye)
Countries
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Other Identifiers
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UPC-Comillas
Identifier Type: -
Identifier Source: org_study_id
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