Effects of Taurine Supplementation on Repetitive Sprint Performance and Exhaustion Time in College Students Under High-Temperature and High-Humidity Conditions

NCT ID: NCT06824571

Last Updated: 2025-02-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

16 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-12-01

Study Completion Date

2025-01-09

Brief Summary

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This study is designed to evaluate the effects of acute pre-exercise taurine supplementation at different doses on the performance of college students during exhaustive exercise and subsequent repetitive sprint (RS) activities in a high-temperature, high-humidity environment. Sixteen college students (8 male, 8 female) will participate in a single-blind, randomized, crossover-controlled trial. Participants will be divided into four groups: high-dose taurine (6g), medium-dose taurine (4g), low-dose taurine (1g), and placebo. Key performance metrics such as peak power (PP), mean power (MP), fatigue index (FI), exhaustion time (ET), reverse vertical jump height, heart rate (HR), blood lactate (BLA), and ratings of perceived exertion (RPE) will be measured.

The objective of this study is to assess how taurine supplementation influences exercise performance under these challenging environmental conditions. This study will help to better understand taurine's potential effects on exercise performance and contribute to nutritional strategies for athletes exposed to extreme conditions.

Detailed Description

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This study is designed to evaluate the effects of taurine supplementation on exercise performance under extreme environmental conditions of high temperature and high humidity. The primary goal is to investigate whether taurine supplementation can enhance performance during exhaustive exercise and subsequent repetitive sprints (RS). Sixteen college students (8 male, 8 female) will participate in a single-blind, randomized, crossover-controlled trial. Participants will be divided into four groups receiving either high-dose (6g), medium-dose (4g), low-dose (1g) taurine supplementation, or placebo.

The study will involve a protocol with exhaustive exercise followed by six repetitive sprints. Performance metrics such as peak power (PP), mean power (MP), and fatigue index (FI) will be recorded. Additionally, physiological parameters, including heart rate (HR) and blood lactate (BLA), as well as subjective measures like ratings of perceived exertion (RPE), will be monitored. A standardized measurement protocol will be used to ensure consistency and accuracy across trials.

Conditions

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Exercise Performance in Extreme Environments

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

This study utilized a single-blind, randomized, crossover-controlled design to evaluate the effects of taurine supplementation at varying doses (6g, 4g, 1g) and placebo on exercise performance under high-temperature and high-humidity conditions. Each participant received all four interventions (high-dose, medium-dose, low-dose, and placebo) in randomized order, with a washout period between treatments to minimize carryover effects. This design allows each participant to serve as their own control, enhancing the precision of the comparisons across conditions.
Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

SINGLE

Participants
The study employed a single-blind design where participants were masked to the intervention assignments. This means that participants were unaware of whether they received high-dose taurine (6g), medium-dose taurine (4g), low-dose taurine (1g), or placebo. The care providers and investigators were aware of the intervention assignments to ensure proper administration and data collection.

Study Groups

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High-Dose Taurine Group (6g)

Participants in this arm will receive taurine supplementation at a high dose of 6g, dissolved in water, administered 30 minutes prior to exercise.

High-Dose Taurine Supplementation (6g)

Group Type EXPERIMENTAL

High-Dose Taurine Supplementation (6g)

Intervention Type DIETARY_SUPPLEMENT

Participants will receive taurine supplementation at a high dose of 6g. The taurine will be provided in powder form, dissolved in water, and administered 30 minutes prior to exercise. This intervention is designed to evaluate the effects of high-dose taurine supplementation on exercise performance, fatigue resistance, and recovery under high-temperature and high-humidity conditions.

Medium-Dose Taurine Group (4g)

Participants in this study arm will receive a medium dose of taurine supplementation (4g) in powder form, dissolved in water, administered once 30 minutes prior to exercise. This intervention aims to evaluate the effects of medium-dose taurine on exercise performance, fatigue resistance, and recovery under high-temperature and high-humidity conditions. The study will measure key parameters, including peak power (PP), mean power (MP), fatigue index (FI), exhaustion time (ET), reverse vertical jump values, heart rate (HR), blood lactate (BLA), and ratings of perceived exertion (RPE). This arm is distinguished by the administration of a moderate taurine dosage compared to the high-dose and low-dose groups.

Group Type EXPERIMENTAL

Medium-Dose Taurine Supplementation (4g)

Intervention Type DIETARY_SUPPLEMENT

Participants will receive taurine supplementation at a medium dose of 4g. The taurine will be provided in powder form, dissolved in water, and administered 30 minutes prior to exercise. This intervention is designed to evaluate the effects of medium-dose taurine supplementation on exercise performance, fatigue resistance, and recovery under high-temperature and high-humidity conditions.

Low-Dose Taurine Group (1g)

Participants in this study arm will receive a low dose of taurine supplementation (1g) in powder form, dissolved in water, administered once 30 minutes prior to exercise. This intervention aims to assess the effects of low-dose taurine on exercise performance, fatigue resistance, and recovery under high-temperature and high-humidity conditions. The study will measure multiple parameters, including peak power (PP), mean power (MP), fatigue index (FI), exhaustion time (ET), reverse vertical jump values, heart rate (HR), blood lactate (BLA), and ratings of perceived exertion (RPE). This arm is distinguished by the administration of a smaller taurine dosage compared to the medium-dose and high-dose groups.

Group Type EXPERIMENTAL

Low-Dose Taurine Supplementation (1g)

Intervention Type DIETARY_SUPPLEMENT

Participants will receive taurine supplementation at a low dose of 1g. The taurine will be provided in powder form, dissolved in water, and administered 30 minutes prior to exercise. This intervention is designed to evaluate the effects of low-dose taurine supplementation on exercise performance, fatigue resistance, and recovery under high-temperature and high-humidity conditions.

Placebo Group

Participants in this study arm will receive a placebo (inactive substance) in powder form, dissolved in water, administered once 30 minutes prior to exercise. This group serves as the control arm to evaluate the effects of taurine supplementation on exercise performance, fatigue resistance, and recovery under high-temperature and high-humidity conditions. The study will measure key parameters, including peak power (PP), mean power (MP), fatigue index (FI), exhaustion time (ET), reverse vertical jump values, heart rate (HR), blood lactate (BLA), and ratings of perceived exertion (RPE). This arm is distinguished by the administration of an inactive placebo, which contains no taurine, to compare against the taurine intervention arms.

Group Type PLACEBO_COMPARATOR

Placebo (0g Taurine)

Intervention Type DIETARY_SUPPLEMENT

Participants will receive a placebo, consisting of an inactive substance (0g taurine). The placebo will be provided in powder form, dissolved in water, and administered 30 minutes prior to exercise. This intervention serves as a control arm to evaluate the effects of taurine supplementation on exercise performance, fatigue resistance, and recovery under high-temperature and high-humidity conditions.

Interventions

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High-Dose Taurine Supplementation (6g)

Participants will receive taurine supplementation at a high dose of 6g. The taurine will be provided in powder form, dissolved in water, and administered 30 minutes prior to exercise. This intervention is designed to evaluate the effects of high-dose taurine supplementation on exercise performance, fatigue resistance, and recovery under high-temperature and high-humidity conditions.

Intervention Type DIETARY_SUPPLEMENT

Medium-Dose Taurine Supplementation (4g)

Participants will receive taurine supplementation at a medium dose of 4g. The taurine will be provided in powder form, dissolved in water, and administered 30 minutes prior to exercise. This intervention is designed to evaluate the effects of medium-dose taurine supplementation on exercise performance, fatigue resistance, and recovery under high-temperature and high-humidity conditions.

Intervention Type DIETARY_SUPPLEMENT

Low-Dose Taurine Supplementation (1g)

Participants will receive taurine supplementation at a low dose of 1g. The taurine will be provided in powder form, dissolved in water, and administered 30 minutes prior to exercise. This intervention is designed to evaluate the effects of low-dose taurine supplementation on exercise performance, fatigue resistance, and recovery under high-temperature and high-humidity conditions.

Intervention Type DIETARY_SUPPLEMENT

Placebo (0g Taurine)

Participants will receive a placebo, consisting of an inactive substance (0g taurine). The placebo will be provided in powder form, dissolved in water, and administered 30 minutes prior to exercise. This intervention serves as a control arm to evaluate the effects of taurine supplementation on exercise performance, fatigue resistance, and recovery under high-temperature and high-humidity conditions.

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* School students
* Aged between 18 and 28 years
* No exercise-related risk, as indicated by a "no" response to all questions in the Physical Activity Readiness Questionnaire (PAR-Q)
* No taurine-based supplements consumed in the last month.

* Individuals with a history of cardiovascular issues, respiratory problems, or any condition that may impair exercise performance
* Participants who did not provide a "no" response to all questions in the Physical Activity Readiness Questionnaire (PAR-Q)
* Participants who consumed taurine-based supplements in the month preceding the study.
Minimum Eligible Age

20 Days

Maximum Eligible Age

26 Days

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Xiaodong Cheng

OTHER

Sponsor Role lead

Responsible Party

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Xiaodong Cheng

Xian Medical University

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Xiaodong Cheng, PhD

Role: PRINCIPAL_INVESTIGATOR

Xi'an Medical University

Locations

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Capital University of Physical Education and Sports

Beijing, Beijing Municipality, China

Site Status

Countries

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China

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Related Links

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https://www.cupes.edu.cn/index.htm

Official website of the Capital University of Physical Education and Sports, where the study was conducted.

Other Identifiers

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No. 2021A43

Identifier Type: -

Identifier Source: org_study_id

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