Influence of Caffeinated and Non-caffeinated Pre-workout Supplements on Resistance Exercise Performance

NCT ID: NCT04712578

Last Updated: 2021-06-03

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 24 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2021-02-23
• Study Completion Date: 2021-05-11

Brief Summary

This study is a randomized, double-blind, placebo-controlled crossover trial examining the effects of caffeinated and non-caffeinated pre-workout supplements on resistance exercise performance. Resistance-trained adults will be randomly assigned to complete three study conditions (caffeinated pre-workout, non-caffeinated pre-workout, and placebo) in one of the six possible condition orders. During each condition, participants will report to the laboratory for ingestion of the assigned beverage and subsequent muscular performance testing. Major performance outcomes will be force production variables from a mechanized squat device and maximal strength and muscular endurance on the bench press and leg press exercises.

Conditions

Resistance Training; Caffeine; Dietary Supplements

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: CROSSOVER
• Primary Study Purpose: OTHER
• Blinding Strategy: TRIPLE

Study Groups

Caffeinated Pre-workout Supplement

This arm will consist of ingestion of the commercially available, caffeinated Pulse pre-workout, manufactured by Legion Athletics, Inc.

Group Type: EXPERIMENTAL

Caffeinated pre-workout supplement

Intervention Type: DIETARY_SUPPLEMENT

The intervention will consist of consuming a standardized meal followed by one serving of the commercially available Pulse caffeinated pre-workout supplement (Legion Athletics, Inc.).

Non-Caffeinated Pre-Workout Supplement

This arm will consist of ingestion of the commercially available, non-caffeinated Pulse pre-workout, manufactured by Legion Athletics, Inc.

Group Type: ACTIVE_COMPARATOR

Non-caffeinated pre-workout supplement

Intervention Type: DIETARY_SUPPLEMENT

The intervention will consist of consuming a standardized meal followed by one serving of the commercially available Pulse non-caffeinated pre-workout supplement (Legion Athletics, Inc.).

Placebo

This arm will consist of a flavor-matched placebo beverage without the active components contained in the supplements administered in the other study arms.

Group Type: PLACEBO_COMPARATOR

Placebo

Intervention Type: DIETARY_SUPPLEMENT

The intervention will consist of consuming a standardized meal followed by a placebo beverage.

Interventions

Caffeinated pre-workout supplement

The intervention will consist of consuming a standardized meal followed by one serving of the commercially available Pulse caffeinated pre-workout supplement (Legion Athletics, Inc.).

Intervention Type: DIETARY_SUPPLEMENT

Non-caffeinated pre-workout supplement

The intervention will consist of consuming a standardized meal followed by one serving of the commercially available Pulse non-caffeinated pre-workout supplement (Legion Athletics, Inc.).

Intervention Type: DIETARY_SUPPLEMENT

Placebo

The intervention will consist of consuming a standardized meal followed by a placebo beverage.

Intervention Type: DIETARY_SUPPLEMENT

Other Intervention Names

Legion Athletics Pulse Pre-workout Supplement; Legion Athletics Pulse Pre-workout Supplement

Eligibility Criteria

Inclusion Criteria

• Between the ages of 18 and 40;
• Body mass between 50 - 100 kg (110-220 lb)
• Generally healthy (defined as an absence of any disease or medical condition which could potentially be negatively affected by consumption of the commercially available dietary supplements or performance of exercise, including but not limited to musculoskeletal or cardiovascular diseases).
• Resistance-trained, defined as completing 2+ resistance training sessions per week for at least three months prior to screening.
• Participants must have reported regular training of the lower body through a multi-joint exercise such as the squat or leg press at least once weekly during the three-month period prior to screening.
• Participants must have reported regular training of the bench press or chest press variation at least once weekly during the three-month period prior to screening.
• Female participants will be required to bench press ≥ 0.5 x body mass and leg press ≥ 1.75 x body mass during initial 1RM assessments to be eligible for this study.
• Male participants will be required to bench press ≥ 1.0 x body mass and leg press ≥ 3.0 x body mass to be eligible.
• Regular caffeine consumption (due to the presence of caffeine in the commercially available dietary supplement). This will be defined as an average self-reported daily intake of 250+ mg of caffeine, which is equivalent to approximately 2.5 cups of coffee.

• Pregnant or breastfeeding (for female participants)
• Taking prescription medication which could reasonably make participation unsafe for the participant or influence study outcomes
• An inability to complete resistance exercise due to injury or medical condition
• Self-reported caffeine sensitivity, as indicated by unwanted side effects when caffeine is consumed.
• Allergy to any of the ingredients in the test beverages or standardized breakfast.
• Current use of anabolic steroids
• Presence of a pacemaker or other implanted electrical device.
• Unwillingness to wear the provided surgical mask during all testing procedures.

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 40 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Legion Athletics, Inc

UNKNOWN

Sponsor Role: collaborator

Texas Tech University

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

Department of Kinesiology & Sport Management

Lubbock, Texas, United States

Countries

United States

Other Identifiers

20-1299

Identifier Type: OTHER

Identifier Source: secondary_id

IRB2020-813

Identifier Type: -

Identifier Source: org_study_id