Creatine Supplementation At Simulated Altitude

NCT ID: NCT06489587

Last Updated: 2024-07-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-06-25

Study Completion Date

2026-06-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Creatine supplementation has been shown to increase exercise performance at sea level. The goal of this study is to determine the effects of creatine supplementation on exercise performance at simulated altitude.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Military personnel often encounter harsh environments such as high altitudes and hypoxic conditions, leading to significant constraints on their exercise capacity and performance. At sea-level creatine supplementation increases exercise performance; however no experimental studies have examined the effect of creatine supplementation at simulated altitude. The overall objective of this study is to investigate the effects of creatine supplementation on exercise performance, via a repeated sprints test (Wingate Test) after a 2-day supplementation period, compared to a placebo group.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Exercise Performance

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Randomized study to two arms: 1) creatine supplementation, 2) glucose supplementation
Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors
Research staff collecting data will be masked to intervention

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Placebo Supplementation

Participants given Placebo (20 grams of glucose) daily in 5-gram servings (4 capsules), 4 times per day for 2 days.

Group Type ACTIVE_COMPARATOR

Placebo

Intervention Type DIETARY_SUPPLEMENT

Participants given 40 grams of glucose in total to be taken over 2 days, in 5-gram servings (4 capsules), 4 times per day.

Creatine Supplementation

Participants given Creatine (20 grams of glucose) daily in 5-gram servings (4 capsules), 4 times per day for 2 days.

Group Type EXPERIMENTAL

Creatine

Intervention Type DIETARY_SUPPLEMENT

Participants given 40 grams of creatine in total to be taken over 2 days, in 5-gram servings (4 capsules), 4 times per day.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Placebo

Participants given 40 grams of glucose in total to be taken over 2 days, in 5-gram servings (4 capsules), 4 times per day.

Intervention Type DIETARY_SUPPLEMENT

Creatine

Participants given 40 grams of creatine in total to be taken over 2 days, in 5-gram servings (4 capsules), 4 times per day.

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* 18-40 years old
* BMI 18.5 to 40 kg/m2
* Habitually active (\>150 minutes per week of moderate-vigorous physical activity)

Exclusion Criteria

* Pregnant or trying to become pregnant
* Recent use of creatine supplementation
* Supplemental allergies
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

California Polytechnic State University-San Luis Obispo

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Todd Hagobian

Chair and Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Todd Hagobian, PhD

Role: PRINCIPAL_INVESTIGATOR

California Polytechnic State University-San Luis Obispo

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

California Polytechnic State University

San Luis Obispo, California, United States

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

United States

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Todd Hagobian, PhD

Role: CONTACT

8057567511

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Todd Hagobian, PhD

Role: primary

805-756-7511

Eric Benso, BS

Role: backup

805-756-7525

Provided Documents

Download supplemental materials such as informed consent forms, study protocols, or participant manuals.

Document Type: Study Protocol

View Document

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

2023-233

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Betaine Effect in Speed-strength Athletes
NCT03702205 UNKNOWN PHASE2/PHASE3
HBOT and Exercise Recovery
NCT05924035 WITHDRAWN NA