The Influence of Caffeine Supplementation on Specific Performance and Training Activities

NCT ID: NCT03822663

Last Updated: 2024-04-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

26 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-05-15

Study Completion Date

2023-12-20

Brief Summary

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The purpose of this study is to verify the effect of acute caffeine (CAF) and placebo (PLA) supplementation on physical capacity and discipline-specific exercise performance in athletes, in a randomised, double-blind, placebo-controlled crossover trial.

Detailed Description

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Caffeine (CAF) is often proposed as an ergogenic agent, especially during high-intensity efforts. CAF supplementation may reduce effort-induced multi-faceted symptoms of fatigue and can improve psychomotor functions (like agility or decision-making processes), which is required during the intermittent high-intensity efforts in combat sports and speed-strength disciplines. Moreover, it is suggested that CAF treatment is associated with increased glycolytic activity during simulated or real training/competition bouts, which results in performance and physical capacity improvement.

However, there are hardly any data on the individual CAF-induced and dose-dependent changes in physical capacity and discipline-specific performance in combat sports and speed-strength disciplines. Therefore, the study aims to examine the effect of acute, different-dose CAF ingestion on physical capacity and discipline-specific performance in combat sports and speed-strength athletes, in a randomized, double-blind, placebo-controlled crossover trial.

Conditions

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Supplementation Sports

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Caffeine supplementation

Group taking oral CAF (Caffeine) supplementation in a different-dose crossover regimen.

Group Type EXPERIMENTAL

Caffeine supplementation

Intervention Type DIETARY_SUPPLEMENT

The experimental procedure for each athlete includes an acute CAF supplementation in a different-dose crossover regimen in order to assess whether the dose affects the actual physical capacity and discipline-specific exercise performance (doses: 3.0-, 6.0- and 9.0 mg/kg of body mass, respectively). CAF (pure pharmaceutical caffeine) will be administered in the dissolved form. On testing days, the supplements will be taken 70 min before physical and exercise capacity test session. Between the CAF and PLA or a PLA and CAF treatments, a minimum 7-day washout period will be introduced.

Placebo treatment

Group taking oral supplementation with placebo.

Group Type PLACEBO_COMPARATOR

Placebo treatment

Intervention Type DIETARY_SUPPLEMENT

The experimental procedure for each athlete will include PLA supplementation. Placebo will be administered in the dissolved form. On testing days, the PLA will be taken 70 min before physical and exercise capacity test session. Between the PLA and CAF or a CAF and PLA treatments, a minimum 7-day washout period will be introduced.

Interventions

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Caffeine supplementation

The experimental procedure for each athlete includes an acute CAF supplementation in a different-dose crossover regimen in order to assess whether the dose affects the actual physical capacity and discipline-specific exercise performance (doses: 3.0-, 6.0- and 9.0 mg/kg of body mass, respectively). CAF (pure pharmaceutical caffeine) will be administered in the dissolved form. On testing days, the supplements will be taken 70 min before physical and exercise capacity test session. Between the CAF and PLA or a PLA and CAF treatments, a minimum 7-day washout period will be introduced.

Intervention Type DIETARY_SUPPLEMENT

Placebo treatment

The experimental procedure for each athlete will include PLA supplementation. Placebo will be administered in the dissolved form. On testing days, the PLA will be taken 70 min before physical and exercise capacity test session. Between the PLA and CAF or a CAF and PLA treatments, a minimum 7-day washout period will be introduced.

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* written consent to participate,
* a current medical clearance to practice sports,
* training experience: at least 2 years,
* minimum of 4 workout sessions (in the discipline covered by the study) a week.

Exclusion Criteria

* current injury,
* any health-related contraindication,
* declared general feeling of being unwell,
* unwilling to follow the study protocol.
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Poznan University of Life Sciences

OTHER

Sponsor Role collaborator

Poznan University of Physical Education

OTHER

Sponsor Role lead

Responsible Party

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Krzysztof Durkalec-Michalski

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Krzysztof Durkalec-Michalski, PhD

Role: PRINCIPAL_INVESTIGATOR

Department of Sports Dietetics, Poznan University of Physical Education, Poznan, Poland

Locations

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Department of Sports Dietetics, Poznan University of Physical Education

Poznan, Wielkopolska, Poland

Site Status

Countries

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Poland

References

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Glowka N, Malik J, Aniola J, Zawieja EE, Chmurzynska A, Durkalec-Michalski K. The effect of caffeine dose on caffeine and paraxanthine changes in serum and saliva and CYP1A2 enzyme activity in athletes: a randomized placebo-controlled crossover trial. Nutr Metab (Lond). 2024 Nov 11;21(1):90. doi: 10.1186/s12986-024-00863-3.

Reference Type DERIVED
PMID: 39529054 (View on PubMed)

Durkalec-Michalski K, Nowaczyk PM, Glowka N, Grygiel A. Dose-dependent effect of caffeine supplementation on judo-specific performance and training activity: a randomized placebo-controlled crossover trial. J Int Soc Sports Nutr. 2019 Sep 5;16(1):38. doi: 10.1186/s12970-019-0305-8.

Reference Type DERIVED
PMID: 31488190 (View on PubMed)

Other Identifiers

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ULS00007

Identifier Type: -

Identifier Source: org_study_id

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