Caffeine and Sodium Bicarbonate Supplementation Effects on Resistance Training Performance
NCT ID: NCT06714331
Last Updated: 2024-12-03
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
EARLY_PHASE1
20 participants
INTERVENTIONAL
2024-08-01
2024-12-10
Brief Summary
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Detailed Description
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All testing will be performed within the laboratory. Participants are instructed to meet the following conditions 24-h before each experimental trial: (i) to avoid vigorous exercise, (ii) to adopt a similar diet and drink intake, (iii) to refrain from the consumption of alcohol, caffeine, and other stimulants.
Measures
For the knee extension measures, EMG activity will be collected from the mid-belly (midway between the anterior superior iliac spine to the superior edge of the patella) of the vastus lateralis and biceps femoris (midway between the gluteal fold and the popliteal space) of the non-dominant leg. Before participants perform the bench press, surface EMG recording electrodes will be placed approximately 3 cm apart over the proximal, lateral segment of the biceps brachii and over the lateral head of the triceps brachii. The distance of the biceps brachii electrodes from the acromion process and the distance of the triceps electrodes from the biceps electrodes will be recorded to ensure accurate replacement for subsequent tests. A thorough skin preparation for all electrodes will include shaving and removal of dead epithelial cells with abrasive pad around the designated areas, followed by cleansing with an isopropyl alcohol swab. EMG will be collected using a Biopac (Biopac Systems Inc.) data acquisition system at a sample rate of 2,000 Hz \[impedance = 2 MΩ, common mode rejection ratio \>110 dB min (50/60 Hz), noise \>5 μV\]. A bandpass filter (10-500 Hz) will be applied prior to digital conversion.
The root mean square (RMS) EMG will be monitored throughout the range of movements for both the bench press and knee extension. The mean RMS EMG will be normalized to the highest pre-test value and reported as a percentage.
A linear position transducer (Chronojump; Boscosystem, Barcelona, Spain) will be attached to the barbell to measure the excursion of the movement, time, and velocity. This device has been previously validated for velocity and power measurements.
Blood lactate levels will be measured with StatStrip Xpress Lactate (SSX) (Nova Biomedical, Waltham, Massachusetts, USA) prior to, during, and after the bench press and knee extension exercises to determine blood-lactate levels of the participants.
The participant's heart rate and rating of perceived exertion will be collected immediately after the completion of each set.
Intervention
During the subsequent three visits, participants will consume the placebo (dextrose), caffeine or sodium bicarbonate. A one week washout period will be allocated between visits. The same quantity will be used during both testing trials to ensure that the supplement is the only variable. The participants will spend 1 hour in a seated resting position after consuming the placebo or supplement. Participants will then utilize the same warm-up as the first visit, 8-10 repetitions at 50% of their body mass.
Testing Procedure
Using a 10RM load, participants will be instructed to complete as many repetitions as possible for each set (6 sets for each exercise) until they can no longer complete a repetition without assistance. Researchers will then record the number of repetitions participants complete during each set. The participant will then undergo a 60-second rest period between each set. After the participant completes the first exercise (e.g., six bench press or knee extension sets), they will undergo a 120-second rest period before beginning the same procedure on the next exercise (i.e., bench press or isoinertial knee extension resistance device). The order of bench press and knee extension exercises will be randomized.
Conditions
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Study Design
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RANDOMIZED
CROSSOVER
BASIC_SCIENCE
TRIPLE
Study Groups
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Caffeine
Caffeine supplement is consumed at 3 time points (120, 90 and 45 minutes prior to testing) with participants drinking 300mL of a caffeine and water solution at each time for a total consumed volume of 900mL .
Caffeine concentration - 3mg/kg or 0.003g/kg
Each solution has MiO Liquid Water Enhancer to mask the taste.
Supplements
Supplements provided to subjects 2 hours prior to testing and drank at 2 hours, 90 minutes and 45 minutes before testing.
Sodium bicarbonate
Sodium bicarbonate supplement is consumed at 3 time points (120, 90 and 45 minutes prior to testing) with participants drinking 300mL of sodium bicarbonate solution at each time for a total consumed volume of 900mL.
Sodium bicarbonate concentration - 0.3g/kg (Arm and Hammer brand)
Each solution has MiO Liquid Water Enhancer to mask the taste.
Supplements
Supplements provided to subjects 2 hours prior to testing and drank at 2 hours, 90 minutes and 45 minutes before testing.
Control
Control solution is MiO + 300mL water at 3 time points (120, 90 and 45 minutes prior to testing) with participants drinking 300mL of control solution at each time for a total consumed volume of 900mL.
Supplements
Supplements provided to subjects 2 hours prior to testing and drank at 2 hours, 90 minutes and 45 minutes before testing.
Interventions
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Supplements
Supplements provided to subjects 2 hours prior to testing and drank at 2 hours, 90 minutes and 45 minutes before testing.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
18 Years
40 Years
ALL
Yes
Sponsors
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Memorial University of Newfoundland
OTHER
Responsible Party
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David George Behm
Professor
Principal Investigators
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David G Behm, PhD
Role: PRINCIPAL_INVESTIGATOR
Memorial University of Newfoundland
Locations
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Memorial University of Newfoundland
St. John's, Newfoundland and Labrador, Canada
Memorial University of Newfoundland
St. John's, Newfoundland and Labrador, Canada
Countries
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Central Contacts
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Facility Contacts
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David G Behm, PhD
Role: primary
Catherine Barret, BKin
Role: backup
Megan Squires, BKin
Role: backup
Karlie Squires, BKin
Role: backup
Colin P Major, BKin
Role: backup
Other Identifiers
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20241611
Identifier Type: -
Identifier Source: org_study_id