Pre-workout Supplement Versus Caffeine on Energy Expenditure.

NCT ID: NCT04539054

Last Updated: 2020-09-04

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 12 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2019-09-01
• Study Completion Date: 2019-12-31

Brief Summary

The primary purpose of this study was to examine the acute effects of a multi-ingredient pre-workout supplement versus an ergogenic dose of caffeine (6 mg/kg) on energy expenditure during low-intensity exercise. The effects of these substances on substrate utilization, gas exchange, and psychological factors were also investigated. Twelve males (mean ± SD: age = 22.8 ± 2.4 years) completed three bouts of 60-min of treadmill exercise at 4.8-6.4 km/hr on separate days after consuming a pre-workout supplement, 6 mg/kg of caffeine, or placebo in a randomized fashion. The pre-workout and caffeine supplements resulted in significantly greater energy expenditure (p < 0.001, p = 0.006, respectively), VO2 (p < 0.001, p = 0.007, respectively), VCO2 (p = 0.006, p = 0.049, respectively), and VE (p < 0.001, p = 0.007, respectively), but not rates of fat or carbohydrate oxidation or respiratory exchange ratio compared to placebo (collapsed across condition). In addition, the pre-workout supplement increased feelings of alertness (p = 0.015) and focus (p = 0.005) 30-minutes post-ingestion and decreased feelings of fatigue (p = 0.014) during exercise compared to placebo (collapsed across condition). Thus, the pre-workout supplement increased energy expenditure and measures of gas exchange to the same extent as 6 mg/kg of caffeine with concomitant increased feelings of alertness and focus and decreased feelings of fatigue.

Conditions

Healthy

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: CROSSOVER
• Primary Study Purpose: TREATMENT
• Blinding Strategy: DOUBLE

Study Groups

Pre-Workout Condition

This condition consisted of the ingestion of one serving of the pre-workout supplement.

Group Type: EXPERIMENTAL

ENGN Shred

Intervention Type: DIETARY_SUPPLEMENT

ENGN Shred is a multi-ingredient pre-workout supplement.

Caffeine Condition

This condition consisted of the ingestion of 6 mg of caffeine per kg of body mass.

Group Type: EXPERIMENTAL

Nutricost caffeine powder

Intervention Type: DIETARY_SUPPLEMENT

Caffeine powder.

Placebo condition

This condition consisted of the ingestion of a placebo.

Group Type: PLACEBO_COMPARATOR

Crystal Light

Intervention Type: DIETARY_SUPPLEMENT

Non-caloric Crystal Light matched for the pre-workout in terms of flavor and consistency.

Interventions

ENGN Shred

ENGN Shred is a multi-ingredient pre-workout supplement.

Intervention Type: DIETARY_SUPPLEMENT

Nutricost caffeine powder

Caffeine powder.

Intervention Type: DIETARY_SUPPLEMENT

Crystal Light

Non-caloric Crystal Light matched for the pre-workout in terms of flavor and consistency.

Intervention Type: DIETARY_SUPPLEMENT

Eligibility Criteria

Inclusion Criteria

• Male

Exclusion Criteria

• history of medical or surgical events, including cardiovascular disease, metabolic, renal, hepatic, or musculoskeletal disorders;
• use of any medications
• use of nutritional supplements
• habitual use of caffeine (≥1 caffeinated beverage per day)
• participation in another clinical trial or investigation of another investigational product within 30 days prior to screening/enrollment.

• Minimum Eligible Age: 19 Years
• Maximum Eligible Age: 29 Years
• Eligible Sex: MALE
• Accepts Healthy Volunteers: Yes

Sponsors

Northern Illinois University

OTHER

Sponsor Role: lead

Responsible Party

Clayton Camic

Associate Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Clayton L Camic, PhD

Role: PRINCIPAL_INVESTIGATOR

Northern Illinois University

Locations

Exercise Physiology Laboratory

DeKalb, Illinois, United States

Countries

United States

Other Identifiers

HS19-0163

Identifier Type: -

Identifier Source: org_study_id