Long-term Intervention Effects of a Personalized, Home-based Exercise Program and Nutritional Advice, Along With the Inclusion of a Pre-workout Multi-ingredient Supplement on the Body Composition, Functional Capacity and Quality of Life of Middle-aged and Older Adults (40-70 Years)

NCT ID: NCT04630977

Last Updated: 2021-12-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

3000 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-01-01

Study Completion Date

2023-05-28

Brief Summary

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The purpose of this study is to analyse the potential benefits of ingesting a commercially available pre-workout multi-ingredient supplement providing \~90 Kcal. for 25g of powder: carbohydrates -isomaltulose, fructose, maltodextrin- 15 g, essential amino-acids -Beta-alanine -L-arginine AKG, L-Leucine, Taurine, L-citrulline- 6.8 g, Creatine monohydrate: 2g, Guarana Extract: 800mg, total caffeine: 160mg, and Magnesium: 112.5mg) vs Placebo CHO intake on body composition, physical performance, Happiness Score (specially designed by our sponsor company, including different self-reported and validated tests on their short form) and every workout: Self-perceived energy feeling and adherence to the intervention.

Detailed Description

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The methodology will follow a Home-based, online, double-blinded, randomised, long-term design. The participants recruited will be active, middle-aged and older healthy adults. The supplement intake will be a Pre-workout supplement intake or a placebo intake. The exercise training will be a Progressive Resistance Training, with sessions of \~1 hour (3 times/week). The intervention will last for a minimum of one year and the possibility to prolong it to another one (two years of intervention) if the adherence to the treatment was higher to the 75% of the participants (of, at least, 85% of the training sessions and supplementation intake).

The outcomes that will be assessed are: Body composition (fat mass and fat-free mass), physical performance (short test designed by Go Fit Lab: single-leg standing balance, upper-body strength - maximum number of push-ups repetitions in 15 seconds -, lower-body mechanical power - vertical jump -, agility/velocity - 30 seconds of static running at maximum velocity -, recovery assessment - 60 seconds monitoring of heart rate after the previous test -), Happiness Score (designed by Go Fit, including different self-reported validated tests, such as: Par-Q+, ACSM Cardiovascular Risk Factors Questionnaire, SF-12 for quality of life and self-perceived health status, PSS-4 Stress and mental health, Pittsburgh Sleeping Quality test, PREDIMED test: adherence to Mediterranean diet eating patterns, and the IPAQ short form), and for every workout: Self-perceived energy feeling (Questionnaire: Energy Level, Fatigue, Alertness and Focus for the Task), Rate of Perceived Exertion (OMNI RES Scale and Borg Scale) and adherence to regular physical exercise practise, healthy nutritional patterns, and supplement intake.

Conditions

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Muscle Loss Obesity Obesity, Abdominal Weight Loss Happiness Quality of Life Self-Perception Stress, Psychological

Keywords

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Weight Loss Body Composition Home-Based Supplement Multi-ingredient

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

One group will intake a pre-workout multi-ingredient supplement. The second group will intake an isocaloric placebo containing only carbohydrates.

The third group (control) will take a non-caloric placebo.
Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors
Every participant will be randomized to any of the groups. The principal investigator will be blinded for the supplement and allocation of the participants until the end of the analysis of the results after the intervention. Therefore, an external and third researcher will send the supplements to every participant and will keep the record of the randomised allocation of each of them until the end of the analysis of the last outcomes assessments collection.

Study Groups

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Multi-Ingredient Pre-workout Supplement

This group of participants will intake a multi-ingredient supplement around \~15 minutes before every workout.

The nutritional information of the supplement is: \~90 Kcal. for 25g of powder: carbohydrates -isomaltulose, fructose, maltodextrin- 15 g, essential amino-acids -Beta-alanine: 2.5g, L-arginine AKG: 2.5g, L-Leucine: 800mg, Taurine: 500mg, L-citrulline: 500mg- 6.8 g, Creatine monohydrate: 2.0g, Guarana Extract: 800mg, total caffeine: 160mg, and Magnesium: 112.5mg.

They will also follow a previously designed progressive resistance training (3 times a week, around 1 hour a day, consisting of different exercises).

Also, they will receive a specific guideline with simple tips to improve their nutritional patterns.

The training sessions and the nutritional guideline will be the same for the three groups.

Group Type EXPERIMENTAL

Multi-ingredient Pre-workout supplement

Intervention Type DIETARY_SUPPLEMENT

Every important issue has been detailed before.

Progressive Resistance Training

Intervention Type OTHER

The information about it has been detailed in advance.

Nutritional Patterns Guideline

Intervention Type BEHAVIORAL

This intervention has also been described in advance.

Isocaloric Placebo

This group of participants will intake an isocaloric (only carbohydrates: Maltodextrin) supplement comparator, around \~15 minutes before every workout.

The nutritional information of the supplement is: \~90 Kcal. for 23g of powder.

They will also follow a previously designed progressive resistance training (3 times a week, around 1 hour a day, consisting of different exercises).

Also, they will receive a specific guideline with simple tips to improve their nutritional patterns.

The training sessions and the nutritional guideline will be the same for the three groups.

Group Type ACTIVE_COMPARATOR

Progressive Resistance Training

Intervention Type OTHER

The information about it has been detailed in advance.

Nutritional Patterns Guideline

Intervention Type BEHAVIORAL

This intervention has also been described in advance.

Control

These participants will drink a non-caloric admixture with the same taste, texture and flavour.

They will also follow a previously designed progressive resistance training (3 times a week, around 1 hour a day, consisting of different exercises).

Also, they will receive a specific guideline with simple tips to improve their nutritional patterns.

The training sessions and the nutritional guideline will be the same for the three groups.

Group Type SHAM_COMPARATOR

Progressive Resistance Training

Intervention Type OTHER

The information about it has been detailed in advance.

Nutritional Patterns Guideline

Intervention Type BEHAVIORAL

This intervention has also been described in advance.

Interventions

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Multi-ingredient Pre-workout supplement

Every important issue has been detailed before.

Intervention Type DIETARY_SUPPLEMENT

Progressive Resistance Training

The information about it has been detailed in advance.

Intervention Type OTHER

Nutritional Patterns Guideline

This intervention has also been described in advance.

Intervention Type BEHAVIORAL

Other Intervention Names

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Preworkout PRT RT Nutrition Healthy Eating

Eligibility Criteria

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Inclusion Criteria

* Healthy adults (no current injuries or illnesses which may interfere with the project).
* Recreationally active adults (a minimum of 3 and a maximum of 5 days of training sessions per week: combining resistance and endurance).

Exclusion Criteria

* Participants younger than 40 or older than 70 years old.
* Participants with hard injuries, disabilities or pathologies.
* People taking medication or other supplements which may interfere with the multi-ingredient pre-workout or the training sessions.
Minimum Eligible Age

40 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Ingesport Health Spa Consulting

UNKNOWN

Sponsor Role collaborator

University of Greenwich

OTHER

Sponsor Role lead

Responsible Party

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Joel Puente

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Fernando J Naclerio, Dr

Role: STUDY_DIRECTOR

University of Greenwich

Locations

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University of Greenwich, Avery Hill Campus, Sparrows Farm. Avery Hill, London., United Kingdom, SE9 2BT

London, Avery Hill, London., United Kingdom

Site Status

Countries

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United Kingdom

Central Contacts

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Joel Puente Fernández, PhD Student

Role: CONTACT

Phone: +34626610821

Email: [email protected]

Fernando J Naclerio, Dr

Role: CONTACT

Phone: +44 (0)20 8331 8441

Email: [email protected]

Other Identifiers

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UGreenwich2

Identifier Type: -

Identifier Source: org_study_id