Chronic Grape Extract in Crosstraining Athletes: A Randomized Crossover Trial

NCT ID: NCT07106281

Last Updated: 2025-08-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-09-01

Study Completion Date

2026-01-31

Brief Summary

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The aim of this study is to investigate the effect of cronic GSE intake in crosstraining may have a favorable impact on biochemical markers, recovery, and performance.

Detailed Description

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Supplementation with certain antioxidant nutrients is a feasible strategy to accelerate recovery from fatigue and prevent exercise-induced oxidative damage. Grape seed extract (GSE) contains flavonoids such as proanthocyanidins, which are potent antioxidants with numerous health benefits. Therefore, optimizing the recovery process after training is essential for athletes engaged in strength and power sports who aim to enhance performance.

Thirty trained CrossFit athletes consumed grape seed extract or a placebo for one week. The training session consisted of a 12-minute strength block, a 13-minute metabolic conditioning (MetCon), and a final 15-minute MetCon. The Rating of Perceived Exertion (RPE), Gastrointestinal Distress Score (GDS), blood pressure and the Perceived Recovery Status scale (RPS) were administered at the beginning of the session and at the end of each segment of the CrossFit session. DOMS was assessed using a visual analog scale at 24 and 48 hours after the CrossFit session.

Conditions

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Performance

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

OTHER

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Grape seed extract

600 mg of Grape seed extract

Group Type EXPERIMENTAL

Grape Seed Extract

Intervention Type DIETARY_SUPPLEMENT

600mg of Grape Seed Extract

Placebo

Preparation of colorants, sweeteners, aromas, and acidulants

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DIETARY_SUPPLEMENT

Placebo

Interventions

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Grape Seed Extract

600mg of Grape Seed Extract

Intervention Type DIETARY_SUPPLEMENT

Placebo

Placebo

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Age: 18-35 years.
* Body mass index: 18.5-30 kg/m2.
* Ability to understand the instructions, objectives, and study protocol.
* Minimum of 3 years of experience in crosstraining, with at least 6 hours of weekly training over the past 3 months.
* Resident on the island of Tenerife.

Exclusion Criteria

* History of a significant adverse cardiovascular event, renal insufficiency, cirrhosis, eating disorder, weight control surgical intervention, or type 2 diabetes mellitus.
* Any chronic pathology in which the intake of nutritional supplements, especially use of antioxidant supplements during the 4 weeks prior to the start of the study.
* Any condition that, in the investigator's judgment, would impair the ability to participate in the study or represent a personal risk to the participant.
* Use of medications that may affect the study results.
* Unstable body weight for 3 months prior to the start of the study (\> 4 kg loss or gain in weight).
* Active tobacco abuse or illicit drug use, or history of treatment for alcohol abuse.
* On a special diet or prescribed for other reasons (e.g., celiac disease).
Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Universidad de La Laguna, San Cristóbal de La Laguna, Santa Cruz de Tenerife, Spain.

UNKNOWN

Sponsor Role collaborator

Universidad de Granada

OTHER

Sponsor Role lead

Responsible Party

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Lucas Jurado-Fasoli

PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Universidad de la Laguna

Santa Cruz de Tenerife, , Spain

Site Status

Countries

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Spain

Central Contacts

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Lucas Jurado-Fasoli, PhD

Role: CONTACT

618375662 ext. +34

Facility Contacts

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Alejandro R. Triviño

Role: primary

616 53 57 61 ext. +34

Other Identifiers

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CROSSUVA

Identifier Type: -

Identifier Source: org_study_id

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