Examining Endogenous Antioxidant Levels in Well Trained Cyclists

NCT ID: NCT02281851

Last Updated: 2020-08-11

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

14 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-07-31

Study Completion Date

2016-05-31

Brief Summary

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This study will investigate whether increased habitual intake of antioxidant supplements effects the concentration of endogenous antioxidants, the response of antioxidants to exercise, and differences in oxidative damage compared to a non-supplemented group.

Detailed Description

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Conditions

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Oxidative Stress

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

OTHER

Study Groups

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Supplemented

The group consists of well-trained cyclists who habitually consume vitamin/antioxidant supplements for a period longer than 6 months

No interventions assigned to this group

Non-supplemented

The group consists of well-trained cyclists who do not consume vitamin/antioxidant supplements

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Male,
* BMI 18.8 29.9 kg/m2
* cycle 3-7 times a week for durations longer than 60 minutes
* cycled for a minimum of 3 years
* accustomed to exhaustive cycling protocols
* healthy (no known cardiovascular or metabolic disease)

Exclusion Criteria

* answering "NO" to any question on the general health questionnaire would result in exclusion from the study
* current participation in another clinical study
* current or recent smoker (last 30 days)
* prescription or non-prescription of anti-inflammatory use \>30 days prior to the experiment commencing or any other medications that in the opinion of the investigator may interfere with redox signalling
Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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University of Birmingham

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Sarah Aldred, MSc PhD

Role: PRINCIPAL_INVESTIGATOR

University of Birmingham

Locations

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School of Sport Exercise and Rehabilitation Sciences, University of Birmingham

Birmingham, West Midlands, United Kingdom

Site Status

Countries

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United Kingdom

Other Identifiers

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13/WM/0226

Identifier Type: OTHER

Identifier Source: secondary_id

125663

Identifier Type: -

Identifier Source: org_study_id

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