Acute Impact of Different Foods and Beverages on Exercise Induced Oxidative Stress and Inflammation

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

42 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-05-17

Study Completion Date

2024-04-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The aim of this research project is to explore the acute impact of specific foods and beverages, which have been shown to be associated with inflammatory processes, mainly in epidemiological studies, on inflammatory and oxidative stress parameters in healthy humans following a high intensity physical workout.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Effect of an Antioxidant-rich Diet During Moderate Altitude Training

NCT03088891

Oxidative Stress Adaptation Reaction Inflammation

COMPLETED NA

The Impact of Dietary Intervention on Oxidative/antioxidant Markers and Gut Microbiota in Athletes

NCT06855979

Non Communicable Diseases

COMPLETED NA

Investigating a Natural Antioxidant Food Product on Oxidative Stress in Recreationally Active Participants

NCT04959006

Oxidative Stress Exercise Recovery

COMPLETED NA

Dietary Macronutrient Manipulation and Substrate Oxidation During Exercise

NCT02605291

Dietary Manipulation

COMPLETED NA

Turmeric and Exercise-Induced Muscle Damage and Oxinflammation

NCT04765527

Muscular Injury

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The aim of this research project is to explore the acute impact of specific foods and beverages, which have been shown to be associated with inflammatory processes, mainly in epidemiological studies, on inflammatory and oxidative stress parameters in healthy humans following a high intensity physical workout. The choice of food will mainly be based on the food groups from the Empirical Dietary Inflammatory Index. For that purpose, forty-two healthy volunteers will be recruited to perform several interventions in order to assess the impact of different nutrient groups or single- foods on oxidative and inflammatory markers. They will be divided into two groups (beverage consumption, n=20 \& plantbased foods, n=22). The intense physical activity serves to induce a physiological stress response in the body, known to be accompanied by an increase in oxidative and inflammatory stress parameters. The idea is that anti- inflammatory or antioxidant nutrients could potentially attenuate this stress response in dependence on their anti- inflammatory or antioxidant potential. The operability of this concept has already been tested. The main benefit of this approach is to get a deeper insight into short term effects of single foods or beverages on inflammatory and prooxidative processes in humans by using short term intense physical activity as a stress model. One major practical aspect of this approach is to assess dietary components with respect to their pro- or anti-inflammatory-/oxidative stress potential regarding e.g. non-communicable diseases such as type 2 diabetes, coronary heart disease or the metabolic syndrome. Furthermore, it could help to reduce inflammation or oxidative stress during or following high intense physical exercise in order to reduce the stress response during training or competition in order to enhance regeneration and to foster the training gain in sports.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Inflammatory Response Oxidative Stress Oxidative Stress Induction

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

acute consumption of anti- and pro- inflammatory foods (n=22) and beverages (n=20) 2 hour prior to intense physical activity in healthy female subjects (in total 42 subjects)

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Impact of GT, coffee, OJ, PGJ, milk, SSB on exercise induced oxidative stress&inflammation

single consumption of one cup of green tea (GT), coffee, orange juice (OJ), pomegranate juice (PGJ), milk and sugar sweetened beverage (SSB) 2 hours prior to a 30-min- HIIT resistance circuit exercise in healthy human subjects

Group Type EXPERIMENTAL

Nutrition

Intervention Type OTHER

acute single dose nutrition intervention

Impact of choc, bcc, fl-oil, blueb., r&w bread on exercise induced oxidative stress&inflammation

single consumption of one proportion of dark chocolate (choc), broccoli (bcc), flaxseed oil, blueberries, white bread and whole grain bread (r = refined \& w = whole grain) 2 hours prior to a 30-min-HIIT resistance circuit exercise in healthy human subjects

Group Type EXPERIMENTAL

Nutrition

Intervention Type OTHER

acute single dose nutrition intervention

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Nutrition

acute single dose nutrition intervention

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* female human subjects
* aged 18-40 years
* no chronical diseases
* not more than 120 minutes of physical activity per week
* no regular resistance training within the past 6 months
* BMI 18.5 - 24.99 kg/m²
* body fat percentage of at least 20%

Exclusion Criteria

* contraindications against physical activity
* anemia
* fructose or lactose intolerance
* smoking
* medications with influence on ROS levels or inflammation
* allergy or intolerance against intervention food/beverages.

Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes