Dietary Macronutrient Manipulation and Substrate Oxidation During Exercise
NCT ID: NCT02605291
Last Updated: 2018-10-11
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
13 participants
INTERVENTIONAL
2016-01-31
2017-06-30
Brief Summary
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Detailed Description
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This study aims to establish the effect of dietary macronutrient manipulation on muscle glycogen levels and substrate oxidation during exercise. Participants will undertake three separate trial periods. During each trial period participants will consume a diet containing different macronutrient compositions. For each of the trials the investigators will assess how the macronutrient composition of the diet affects muscle glycogen level and substrate oxidation during exercise.
Conditions
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Study Design
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RANDOMIZED
CROSSOVER
BASIC_SCIENCE
SINGLE
Study Groups
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Experimental arm 1
One of three 7-day study arms consisting of 3 days of standardised diet followed by 3 days of dietary macronutrient manipulation and 1 day of experimental testing.
Diet with a different macronutrient content A
A diet with altered macronutrient content will be provided to participants on days 4-6 of experimental arm 1.
Interval treadmill running exercise
Participants will perform interval treadmill running exercise on days 4 and 5 of all experimental arms.
Steady state treadmill running exercise
Participants will perform steady state treadmill running exercise on day 7 of all experimental arms.
Experimental arm 2
One of three 7-day study arms consisting of 3 days of standardised diet followed by 3 days of dietary macronutrient manipulation and 1 day of experimental testing.
Diet with a different macronutrient content B
A diet with a different macronutrient content compared to arm 1 will be provided to participants on days 4-6 of experimental arm 2.
Interval treadmill running exercise
Participants will perform interval treadmill running exercise on days 4 and 5 of all experimental arms.
Steady state treadmill running exercise
Participants will perform steady state treadmill running exercise on day 7 of all experimental arms.
Experimental arm 3
One of three 7-day study arms consisting of 3 days of standardised diet followed by 3 days of dietary macronutrient manipulation and 1 day of experimental testing.
Diet with a different macronutrient content C
A diet with a different macronutrient content compared to arms 1 and 2 will be provided to participants on days 4-6 of experimental arm 3.
Interval treadmill running exercise
Participants will perform interval treadmill running exercise on days 4 and 5 of all experimental arms.
Steady state treadmill running exercise
Participants will perform steady state treadmill running exercise on day 7 of all experimental arms.
Interventions
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Diet with a different macronutrient content A
A diet with altered macronutrient content will be provided to participants on days 4-6 of experimental arm 1.
Diet with a different macronutrient content B
A diet with a different macronutrient content compared to arm 1 will be provided to participants on days 4-6 of experimental arm 2.
Diet with a different macronutrient content C
A diet with a different macronutrient content compared to arms 1 and 2 will be provided to participants on days 4-6 of experimental arm 3.
Interval treadmill running exercise
Participants will perform interval treadmill running exercise on days 4 and 5 of all experimental arms.
Steady state treadmill running exercise
Participants will perform steady state treadmill running exercise on day 7 of all experimental arms.
Eligibility Criteria
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Inclusion Criteria
* Non-smoking - currently and for the past 5 years
* Fitness - V̇O2max 40-60 ml/kg/min
* Body mass index (20-25 kg/m2)
Exclusion Criteria
* Participation in another clinical study or receipt of an investigational drug within 30 days of the screening visit.
* Previous participation in this study.
* Recent history (within the last year) of alcohol or other substance abuse.
* An employee of the sponsor or the study site or members of their immediate family.
* Abnormal / extreme habitual dietary practice / intake
* Recent (≤3 months) dietary practice that may be deemed as low and/or high in macronutrients will be excluded.
* The taking of any prescribed medication
18 Years
45 Years
MALE
Yes
Sponsors
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Lucozade Ribena Suntory
INDUSTRY
University of Birmingham
OTHER
Responsible Party
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Principal Investigators
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Gareth A Wallis, PhD
Role: PRINCIPAL_INVESTIGATOR
University of Birmingham
Locations
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School of Sport Exercise and Rehabilitation Sciences, University of Birmingham
Birmingham, , United Kingdom
Countries
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Other Identifiers
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ERN_15-0963
Identifier Type: -
Identifier Source: org_study_id
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