Dietary Nucleotides and Ribose on Muscle Fuel Utilisation
NCT ID: NCT03659890
Last Updated: 2020-03-26
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
13 participants
INTERVENTIONAL
2018-06-28
2020-02-02
Brief Summary
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Previous studies have shown a decrease in ATP levels in the muscle after intense exercise, and this is linked to fatigue. Other studies have also reported benefits of nucleotide and/or ribose supplementation on exercise performance. However, any potential link between ATP metabolism and exercise performance has not been explored.
This study will look at the effects of nucleotide and nucleotide-ribose supplementation in fuel utilisation and performance in skeletal muscle during endurance exercise.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
BASIC_SCIENCE
DOUBLE
Study Groups
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Low nucleotide
2 week supplementation with a low nucleotide mycoprotein drink, with added dextrose
Low nucleotide
2 week, twice daily, supplementation with a nucleotide-depleted mycoprotein drink, with added dextrose
High nucleotide
2 week supplementation with a high nucleotide mycoprotein drink, with added dextrose
High nucleotide
2 week, twice daily, supplementation with a nucleotide-rich mycoprotein drink, with added dextrose
High nucletide + Ribose
2 week supplementation with a high nucleotide mycoprotein drink, with added ribose
High nucletide + Ribose
2 week, twice daily, supplementation with a nucleotide-rich mycoprotein drink, with added ribose
Interventions
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Low nucleotide
2 week, twice daily, supplementation with a nucleotide-depleted mycoprotein drink, with added dextrose
High nucleotide
2 week, twice daily, supplementation with a nucleotide-rich mycoprotein drink, with added dextrose
High nucletide + Ribose
2 week, twice daily, supplementation with a nucleotide-rich mycoprotein drink, with added ribose
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Smokers
* Diagnosed with any metabolic or cardiovascular conditions
* Muscle or bone injuries
* BMI \< 18 or \> 30
18 Years
40 Years
ALL
Yes
Sponsors
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University of Exeter
OTHER
Responsible Party
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Locations
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University of Exeter - St Luke's Campus
Exeter, Devon, United Kingdom
Countries
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Other Identifiers
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171206/B/04
Identifier Type: -
Identifier Source: org_study_id
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