Carbohydrate Use During and Following Exercise

NCT ID: NCT01709617

Last Updated: 2012-10-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

17 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-11-30

Study Completion Date

2014-01-31

Brief Summary

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Carbohydrates are an integral component of sports nutrition. Providing carbohydrate (CHO) during exercise delays the onset of fatigue and improves exercise performance by maintaining high rates of CHO oxidation. Traditionally, glucose, or glucose polymers have been the preferential CHO source found in sports drinks. However, during the intestinal absorption of large amounts of glucose (\>1.2 g/min), sodium-dependent glucose transporters (SGLT1) may become fully saturated, potentially limiting the rate of exogenous CHO oxidation. In an effort to evade this limitation, research has suggested using multiple transportable carbohydrates in the composition of sports drinks. Multiple transportable carbohydrates are combinations of simple sugars that use different intestinal transporters during the absorption process. Ingesting multiple transportable carbohydrates may enhance the capacity for total intestinal CHO absorption, leading to an increase in the rate of exogenous CHO oxidation. Our purpose will be to examine the disaccharide sucrose in it's ability to provide exogenous fuel during and following prolonged exercise.

Detailed Description

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Conditions

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Carbohydrate Oxidation and Glycogen Utilization During and Following Exercise

Keywords

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carbohydrate, glycogen, glucose

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Glucose-glucose

Glucose ingestion

Group Type EXPERIMENTAL

Carbohydrate ingestion

Intervention Type DIETARY_SUPPLEMENT

Various types of carbohydrate ingested during and following exercise

Glucose-Fructose

glucose-fructose ingestion

Group Type ACTIVE_COMPARATOR

Carbohydrate ingestion

Intervention Type DIETARY_SUPPLEMENT

Various types of carbohydrate ingested during and following exercise

disaccharide

Disaccharide ingestion

Group Type ACTIVE_COMPARATOR

Carbohydrate ingestion

Intervention Type DIETARY_SUPPLEMENT

Various types of carbohydrate ingested during and following exercise

Interventions

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Carbohydrate ingestion

Various types of carbohydrate ingested during and following exercise

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Healthy
* Male
* 18 - 40 years of age
* Endurance trained cyclist/triathlete
* VO2 max ≥ 50 ml/kg/min
* BMI \< 25 kg/m2

Exclusion Criteria

* Use of medication
* Smoking
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Maastricht University Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Luc van Loon, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Maastricht University

Locations

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Maastricht University

Maastricht, Limburg, Netherlands

Site Status

Countries

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Netherlands

Central Contacts

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Naomi Cermak, Ph.D.

Role: CONTACT

Phone: 31433881393

Email: [email protected]

Facility Contacts

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Role: primary

Other Identifiers

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12-3-048

Identifier Type: -

Identifier Source: org_study_id