Stem Cell Recruitment in Exercised Skeletal Muscles of Older Women by Phytosteroid Rg1
NCT ID: NCT07093190
Last Updated: 2025-07-30
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
11 participants
INTERVENTIONAL
2022-03-18
2025-07-01
Brief Summary
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The main questions to be answered are:
* Does Rg1 supplementation alter serum sex hormone levels in recovery from exercise?
* Does Rg1 supplementation influence bone marrow stem cell differentiation in skeletal muscles of older women?
Participants will:
* Pre-test body composition, maximal leg strength, blood and muscle tissue.
* One hour after taking the supplement, participants will perform 4 sets of 10 repetitions of 70% of maximal strength (1RM) leg press and have two thigh muscle biopsies (0 and 24 h after exercise).
* Repeat the protocol one month later on the alternative supplement. Researchers will understand whether Rg1 improves recovery response to resistance exercise in post-menopausal women.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
BASIC_SCIENCE
TRIPLE
Study Groups
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exercise following Rg1 consumption
1 hour following the consumption of the Rg1 supplement, participants performed exercise intervention before muscle biopsies were taken.
exercise following Rg1 consumption
The effect of Rg1 on exercised skeletal muscle in older women
exercise only following placebo consumption
Crossover trial with placebo supplementation consumed before exercise
Placebo
Resistance exercise performed 1 hour following placebo consumption
Interventions
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exercise following Rg1 consumption
The effect of Rg1 on exercised skeletal muscle in older women
Placebo
Resistance exercise performed 1 hour following placebo consumption
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
60 Years
70 Years
FEMALE
Yes
Sponsors
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University of Taipei
OTHER
Responsible Party
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Chia-Hua Kuo
Professor
Principal Investigators
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Chia-hua Kuo, PhD
Role: PRINCIPAL_INVESTIGATOR
University of Taipei
Locations
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University of Taipei
Taipei, Taipei, Taiwan
Countries
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References
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Glaziou P, Martin PM. Study of factors that influence the clinical response to ciguatera fish poisoning. Toxicon. 1993 Sep;31(9):1151-4. doi: 10.1016/0041-0101(93)90130-b.
Other Identifiers
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NSTC 110-2622-H-845-004
Identifier Type: OTHER_GRANT
Identifier Source: secondary_id
13A1-CG-CO-05-2426-3
Identifier Type: OTHER_GRANT
Identifier Source: secondary_id
IRB-2021-045
Identifier Type: -
Identifier Source: org_study_id
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