Inspired Oxygen on Oxidative Stress and Breath Volatile Organic Compound Composition in Healthy Volunteers
NCT ID: NCT02577692
Last Updated: 2018-03-08
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
UNKNOWN
NA
20 participants
INTERVENTIONAL
2016-05-31
2019-11-30
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
This study aims to investigate the effects of a high inspiratory oxygen fraction on oxidative stress in healthy volunteers. The primary outcome is the appearance of exhaled breath biomarkers of oxidative stress by electrochemical sensors and ion mobility mass spectrometry. Secondary outcomes are changes in oxidative stress biomarkers in blood and their relationship to breath biomarkers.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Molecular Hydrogen Inhalation: Effects on Health, Exercise Capacity and Inflammatory Response - in Vivo/in Vitro Studies
NCT07130942
Effect of an Antioxidant-rich Diet During Moderate Altitude Training
NCT03088891
The Impact of Dietary Intervention on Oxidative/antioxidant Markers and Gut Microbiota in Athletes
NCT06855979
Acute Impact of Different Foods and Beverages on Exercise Induced Oxidative Stress and Inflammation
NCT05242978
Placebo Controlled Study for Characterisation of Immunological Effects and Safety of Active O2
NCT01333930
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
CROSSOVER
BASIC_SCIENCE
NONE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Oxygen
Day 1: breathing of 100% oxygen; Day 2: ambient air breathing
Oxygen
breathing oxygen
Ambient
breathing ambient air
Ambient
Day 1: breathing of 100% oxygen; Day 2: ambient air breathing
Oxygen
breathing oxygen
Ambient
breathing ambient air
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Oxygen
breathing oxygen
Ambient
breathing ambient air
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
Exclusion Criteria
* any pulmonary disease
* any heart disease
* any chemotherapy in the past
* any kind of daily medication
25 Years
65 Years
MALE
Yes
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Airbus Defence and Space
INDUSTRY
DLR German Aerospace Center
OTHER
Klinikum der Universitaet Muenchen, Grosshadern
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Michael Dolch
Dr. med.
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Michael E Dolch, MD
Role: PRINCIPAL_INVESTIGATOR
Klinikum der Universitaet Muenchen - Campus Grosshadern
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Department of Aneshtesiology, University Hospital of Munich
München, , Germany
Countries
Review the countries where the study has at least one active or historical site.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
eN-2015-1.0
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.