Effect of an Antioxidant-rich Diet During Moderate Altitude Training

NCT ID: NCT03088891

Last Updated: 2017-03-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

35 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-10-31

Study Completion Date

2015-11-30

Brief Summary

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Athletes, especially in endurance sports, are at increased risk of oxidative stress and inflammation-related diseases and injuries. The production of reactive oxygen and nitrogen species (RONS) and inflammatory markers increase during exercise and especially during altitude training. Antioxidant supplementation is commonly used among athletes in the belief that it prevents oxidative stress and oxidative damage. A transient increase of RONS is however necessary to activate signaling cascades initiating training adaptation. Antioxidant supplementation has been shown to inhibit the exercise effects in several independent studies, possibly by interfering/reducing the signal cascades initiated by RONS. However, it is unknown whether a high intake of antioxidant rich foods can affect the amount of RONS, inflammation markers and/or training adaptation. The investigators want to examine whether an increased intake of natural antioxidants in the form of antioxidant-rich foods fruits, vegetables and berries, in line with the official Norwegian dietary advice can affect antioxidant status, immune function and training adaptation associated with altitude training in Norwegian elite athletes.

Detailed Description

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Conditions

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Oxidative Stress Adaptation Reaction Inflammation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Antioxidant-rich snacks

The participants received antioxidant-rich snacks every day during 21 days of moderate altitude training (2300 meters above sea level). The snack included fruits and vegetable smoothies, dark chocolate, walnuts, dried fruits and berries.

Group Type EXPERIMENTAL

Antioxidant-rich snacks

Intervention Type OTHER

Bama Smoothies (Bama, Oslo, Norway), Freia Premium Dark Chocolate (Freia, Oslo, Norway), Walnuts (Eldorado, Norway), Dried fruits and berries (Cranberries, Gojiberries, apricots)(Bama, Oslo, Norway and Rema 1000, Norway)

Control snacks

The participants received antioxidant-depleted snacks every day during 21 days of moderate altitude training (2300 meters above sea level). The snack included milkshake, and other milk-based drinks, biscuits (both sweet and salty), white chocolate.

Group Type PLACEBO_COMPARATOR

Control snacks

Intervention Type OTHER

Milkshake (Tine, Oslo, Norway), YT restitusjonsdrikk (Tine, Oslo, Norway), Bixit (Sætre, Oslo, Norway), Ritz (Mondelez, Oslo, Norway), White chololate (Freia, Oslo, Norway)

Interventions

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Antioxidant-rich snacks

Bama Smoothies (Bama, Oslo, Norway), Freia Premium Dark Chocolate (Freia, Oslo, Norway), Walnuts (Eldorado, Norway), Dried fruits and berries (Cranberries, Gojiberries, apricots)(Bama, Oslo, Norway and Rema 1000, Norway)

Intervention Type OTHER

Control snacks

Milkshake (Tine, Oslo, Norway), YT restitusjonsdrikk (Tine, Oslo, Norway), Bixit (Sætre, Oslo, Norway), Ritz (Mondelez, Oslo, Norway), White chololate (Freia, Oslo, Norway)

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* National team athletes, summer endurance sports

Exclusion Criteria

* Allergies in conflict with the intervention foods
* Use of medication that could affect training and performance
* Injuries that could affect training and performance
Minimum Eligible Age

16 Years

Maximum Eligible Age

42 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Norwegian School of Sport Sciences

OTHER

Sponsor Role collaborator

Norwegian Olympic Federation, Oslo, Norway

UNKNOWN

Sponsor Role collaborator

University of Oslo

OTHER

Sponsor Role lead

Responsible Party

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Rune Blomhoff

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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University of Oslo

Oslo, , Norway

Site Status

Norwegian Olympic Federation

Oslo, , Norway

Site Status

Countries

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Norway

References

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Koivisto-Mork AE, Paur I, Paulsen G, Garthe I, Raastad T, Bastani NE, Blomhoff R, Bohn SK. Dietary Adjustments to Altitude Training in Elite Endurance Athletes; Impact of a Randomized Clinical Trial With Antioxidant-Rich Foods. Front Sports Act Living. 2020 Aug 26;2:106. doi: 10.3389/fspor.2020.00106. eCollection 2020.

Reference Type DERIVED
PMID: 33345095 (View on PubMed)

Other Identifiers

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ALTAX

Identifier Type: -

Identifier Source: org_study_id

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