Regulation of Metabolism and Ion Handling

NCT ID: NCT03317704

Last Updated: 2020-09-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-10-25

Study Completion Date

2020-05-20

Brief Summary

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This study investigates the relation between ion-handling (K+) and fatigue development during exercise. Before and after a 6-week period of high intensity interval training, performance and ion-handling is assessed in young adults. In addition, mitochondrial function is examined.

Detailed Description

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Conditions

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Healthy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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speed endurance training (SET)

Training 6 weeks 3 times pr. week

Group Type ACTIVE_COMPARATOR

Speed endurance training

Intervention Type BEHAVIORAL

Speed endurance training

Controls

Asked to continue their usual life style

Group Type NO_INTERVENTION

No interventions assigned to this group

speed endurance training (SET) II

Training 6 weeks 3 times pr. week

Group Type ACTIVE_COMPARATOR

Speed endurance training

Intervention Type BEHAVIORAL

Speed endurance training

Interventions

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Speed endurance training

Speed endurance training

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Healthy men
* 45-55 ml/kg/min
* BMI 19-26 kg/m2
* Normal ECG (assessed by MD)

Exclusion Criteria

* Allergic to n-acetylcystine (NAC) or digoxin
* Severe side effects from NAC or digoxin
* Chronic diseases (assessed by MD to be a potential hazard or to interfere with outcome measures)
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Morten Hostrup, PhD

OTHER

Sponsor Role lead

Responsible Party

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Morten Hostrup, PhD

Assistant Professor

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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University of Copenhagen

Copenhagen, , Denmark

Site Status

Countries

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Denmark

Other Identifiers

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SET-NAC

Identifier Type: -

Identifier Source: org_study_id

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