Study of Pomegranate Juice in the Modulation of Oxidative Stress Markers in Endurance-based Athletes

NCT ID: NCT02293486

Last Updated: 2014-11-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

EARLY_PHASE1

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-08-31

Study Completion Date

2013-02-28

Brief Summary

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The purpose of this study is to evaluate modifications of plasma protein carbonyls and malondialdehyde levels in endurance-based athletes after three weeks of pomegranate juice consumption.

Detailed Description

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Conditions

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Oxidative Stress

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Control

Arm that followed all the protocols with the exception of the pomegranate juice intake.

Group Type NO_INTERVENTION

No interventions assigned to this group

Pomegranate Juice

Arm that followed all the protocols and the pomegranate juice intake.

Group Type EXPERIMENTAL

Pomegranate juice

Intervention Type DIETARY_SUPPLEMENT

Intake of 200 ml of pomegranate juice or pomegranate juice dilution during 21 days after exercise.

Pomegranate Juice Dilution

Arm that followed all the protocols and the pomegranate juice dilution (1:1) intake.

Group Type EXPERIMENTAL

Pomegranate juice

Intervention Type DIETARY_SUPPLEMENT

Intake of 200 ml of pomegranate juice or pomegranate juice dilution during 21 days after exercise.

Interventions

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Pomegranate juice

Intake of 200 ml of pomegranate juice or pomegranate juice dilution during 21 days after exercise.

Intervention Type DIETARY_SUPPLEMENT

Other Intervention Names

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Zumo de Granada Vitalgrana

Eligibility Criteria

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Inclusion Criteria

* Perform specific endurance training sessions
* More than 1 hour per session and more than 3 sessions per week
* Have participated recently in a half marathon or similar event

Exclusion Criteria

* Intake of antioxidant or anti-inflammatory supplementation
* Present a chronic disorder
* Non-smoker
* No-alcoholic beverage consumption
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Vitalgrana Pomegranate SL

UNKNOWN

Sponsor Role collaborator

Universidad Miguel Hernandez de Elche

OTHER

Sponsor Role lead

Responsible Party

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Néstor Vicente-Salar

PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Enrique Roche, PhD

Role: STUDY_DIRECTOR

University Miguel Hernández

References

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Aviram M, Dornfeld L, Rosenblat M, Volkova N, Kaplan M, Coleman R, Hayek T, Presser D, Fuhrman B. Pomegranate juice consumption reduces oxidative stress, atherogenic modifications to LDL, and platelet aggregation: studies in humans and in atherosclerotic apolipoprotein E-deficient mice. Am J Clin Nutr. 2000 May;71(5):1062-76. doi: 10.1093/ajcn/71.5.1062.

Reference Type RESULT
PMID: 10799367 (View on PubMed)

Trombold JR, Reinfeld AS, Casler JR, Coyle EF. The effect of pomegranate juice supplementation on strength and soreness after eccentric exercise. J Strength Cond Res. 2011 Jul;25(7):1782-8. doi: 10.1519/JSC.0b013e318220d992.

Reference Type RESULT
PMID: 21659887 (View on PubMed)

Other Identifiers

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GRA 01

Identifier Type: -

Identifier Source: org_study_id