Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
30 participants
INTERVENTIONAL
2016-02-29
2017-12-31
Brief Summary
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The aim of this study is to test the impact of a single exposure to exhausting training on microvascular reactivity in healthy sedentary subjects and athletes.
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
BASIC_SCIENCE
NONE
Study Groups
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Sedentary Subjects
Healthy lean sedentary subjects.
Acute Exhausting Exercise (AE)
A single progressive rowing training to maximal exhaustion (AE).
Athletes
Active athletes.
Acute Exhausting Exercise (AE)
A single progressive rowing training to maximal exhaustion (AE).
Interventions
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Acute Exhausting Exercise (AE)
A single progressive rowing training to maximal exhaustion (AE).
Eligibility Criteria
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Inclusion Criteria
* active athletes
* lean sedentary subjects
Exclusion Criteria
* overweight
* hypertension
* coronary artery disease
* diabetes
* hyperlipidaemia
* renal impairment
* cerebrovascular and peripheral artery disease
18 Years
30 Years
ALL
Yes
Sponsors
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Josip Juraj Strossmayer University of Osijek
OTHER
Responsible Party
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Ines Drenjancevic
Vice Dean for Science, Faculty of Medicine Josip Juraj Strossmayer University of Osijek
Principal Investigators
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Ines Drenjancevic, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
Faculty of Medicine, Josip Juraj Strossmayer University of Osijek
Locations
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Faculty of Medicine Osijek, Laboratory for Clinical and Sport Physiology
Osijek, , Croatia
Countries
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Central Contacts
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Facility Contacts
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References
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Cavka A, Cosic A, Jukic I, Jelakovic B, Lombard JH, Phillips SA, Seric V, Mihaljevic I, Drenjancevic I. The role of cyclo-oxygenase-1 in high-salt diet-induced microvascular dysfunction in humans. J Physiol. 2015 Dec 15;593(24):5313-24. doi: 10.1113/JP271631. Epub 2015 Dec 7.
Cavka A, Jukic I, Ali M, Goslawski M, Bian JT, Wang E, Drenjancevic I, Phillips SA. Short-term high salt intake reduces brachial artery and microvascular function in the absence of changes in blood pressure. J Hypertens. 2016 Apr;34(4):676-84. doi: 10.1097/HJH.0000000000000852.
Phillips SA, Das E, Wang J, Pritchard K, Gutterman DD. Resistance and aerobic exercise protects against acute endothelial impairment induced by a single exposure to hypertension during exertion. J Appl Physiol (1985). 2011 Apr;110(4):1013-20. doi: 10.1152/japplphysiol.00438.2010. Epub 2011 Jan 20.
Other Identifiers
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215861071403
Identifier Type: -
Identifier Source: org_study_id
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