Sodium Bicarbonate Supplementation in Athletes

NCT ID: NCT03165357

Last Updated: 2017-05-24

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: PHASE3
• Total Enrollment: 26 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2015-10-10
• Study Completion Date: 2016-04-05

Brief Summary

The purpose of this study was to verify the effect of 10-day sodium bicarbonate (NaHCO3) and placebo (PLA) supplementation on body composition, physical capacity, as well as concentrations of the selected biochemical blood markers in trained athletes, in a randomised, double-blind, placebo-controlled crossover trial.

Detailed Description

Sodium bicarbonate (NaHCO3) was proposed as an ergogenic agent, because it improves high-intensity and resistance exercise performance. Until now the major limitation to NaHCO3 supplementation has been the gastrointestinal (GI) side effects. Therefore, this study aims to examine the effect of chronic, progressive- dose NaHCO3 ingestion on physical capacity, body composition and concentrations of the selected biochemical blood markers in trained athletes, in a randomised, double-blind, placebo-controlled crossover trial.

Conditions

Supplementation; Sport

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: CROSSOVER
• Primary Study Purpose: TREATMENT
• Blinding Strategy: TRIPLE

Study Groups

Sodium bicarbonate

Group taking oral NaHCO3 supplementation in a progressive-dose regimen.

Interventions:

The experimental procedure for each athlete included a 10-day NaHCO3 supplementation in a progressive-dose regimen in order to reduce the likelihood of gastrointestinal side effects (from 37.5 to 150 mg ∙ kg-1). NaHCO3 was administered in the form of unmarked disk-shaped tablets (Alkala T, SANUM, Poland). The tablets were ingested with at least 250 mL of water and could be either swallowed or dissolved in the mouth. On training days the supplements were taken in the morning, in the evening and 1.5 hours before training session. On rest days the supplements were taken in the morning, in the afternoon and in the evening.

Between the 10-day NaHCO3 and PLA or a PLA and NaHCO3 treatments, a 14-day washout period was introduced.

Group Type: EXPERIMENTAL

Sodium bicarbonate supplementation

Intervention Type: DIETARY_SUPPLEMENT

Placebo (maltodextrin)

Group taking oral supplementation with placebo (maltodextrin).

Interventions:

The experimental procedure for each athlete included a 10-day placebo administration. Placebo was ingested with at least 250 mL of water. On training days the supplements were taken in the morning, in the evening and 1.5 hours before training session. On rest days the supplements were taken in the morning, in the afternoon and in the evening.

Between the 10-day NaHCO3 and PLA or a PLA and NaHCO3 treatments, a 14-day washout period was introduced.

Group Type: PLACEBO_COMPARATOR

Placebo treatment

Intervention Type: DIETARY_SUPPLEMENT

Interventions

Sodium bicarbonate supplementation

Intervention Type: DIETARY_SUPPLEMENT

Placebo treatment

Intervention Type: DIETARY_SUPPLEMENT

Eligibility Criteria

Inclusion Criteria

• written consent to participate,
• a current medical clearance to practice sports,
• training experience: at least 2 years (of CrossFit training),
• minimum of 3 workout sessions (CrossFit) a week,
• 20-43 years.

Exclusion Criteria

• current injury,
• any health-related contraindication,
• declared general feeling of being unwell,
• unwilling to follow the study protocol.

• Minimum Eligible Age: 20 Years
• Maximum Eligible Age: 43 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Poznan University of PhysED

INDIV

Sponsor Role: collaborator

Poznan University of Life Sciences

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Jan Jeszka, Professor

Role: STUDY_CHAIR

Department of Hygiene and Human Nutrition, Poznan University of Life Sciences, Poznan, Poland

Locations

Poznan University of Life Sciences, ul.Wojska Polskiego 31

Poznan, Wielkopolska, Poland

Countries

Poland

Other Identifiers

ULS00002

Identifier Type: -

Identifier Source: org_study_id