Probiotics and Overreaching Recovery

NCT ID: NCT04885010

Last Updated: 2021-05-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

16 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-06-01

Study Completion Date

2021-12-31

Brief Summary

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Overloading is a key training principle used by athletes and coaches to improve physical performance. Intensified training periods are therefore commonly incorporated into the course of a regular training season. From a clinical point of view, very intense periods of training are associated with a temporary immunological deficiency which can lead to teh "overreaching syndroms".

During periods of overreaching, nutritional strategies are mainly aimed at ensuring sufficient amounts of energy to support the increase in effort. However less is known about nutritional supplements to attenuated the inflammatory/immunological response to training stress.

Probiotic bacteria are defined as live food ingredients beneficial to the host's health. Numerous health benefits have been attributed to probiotics, including effects on gastrointestinal tract function and disease, immune function, hyperlipidemia, hypertension, and allergic conditions. Studies in the literature on the ergogenic effect of probiotics in athletes are still scarce today. this study aims to explore the potential role of probiotics on performance, recovery from fatigue and immune function during intensive period of training.

Detailed Description

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Conditions

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Fatigue; Muscle, Heart Immunosuppression

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Probiotics

participants will train for 15 days while consuming the dietary supplement. During the last 8 days the intensity of training will increase to induce overreaching.

Group Type EXPERIMENTAL

probiotics

Intervention Type DIETARY_SUPPLEMENT

participants will be given probiotics twice a day for 15 days

Placebo

participants will train for 15 days while consuming the dietary supplement. During the last 8 days the intensity of training will increase to induce overreaching.

Group Type PLACEBO_COMPARATOR

placebo

Intervention Type DIETARY_SUPPLEMENT

participants will be given a placebo twice a day for 15 days

Interventions

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probiotics

participants will be given probiotics twice a day for 15 days

Intervention Type DIETARY_SUPPLEMENT

placebo

participants will be given a placebo twice a day for 15 days

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* age 25-55 years
* Body mass index:\> 18 and \<30 kg / m2
* Stable body weight for at least 3 months
* regular practice of physical activity for at least 2 years

Exclusion Criteria

* Chronic diseases (cardiovascular, hepatic, respiratory, cancer)
* Acute inflammatory states, infections or other pathologies
* Regular use of probiotics
* Use or treatment with steroids (within the previous 3 months)
Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Padova

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Central Contacts

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Tatiana Moro, PhD

Role: CONTACT

0498275306

Other Identifiers

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PARIS

Identifier Type: -

Identifier Source: org_study_id

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