Spirulina Supplementation In Recovery From Damaging Exercise

NCT ID: NCT06391957

Last Updated: 2024-06-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-01-04

Study Completion Date

2024-09-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Exercise can cause muscle damage, leading to a loss in muscle function, increased muscle soreness and inflammation. Evidence supports the use of nutritional strategies to help recovery. Spirulina is a type of algae. It is eaten as a food supplement as it is full of micronutrients, some which provide anti-inflammatory benefits. This work will assess the impact of taking spirulina supplements on recovery from hard exercise. Investigators will measure changes in muscle function, soreness and markers of inflammation.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Damage Muscle

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Spirulina supplement

3g of spirulina supplement three times daily for 5 days.

Group Type EXPERIMENTAL

Spirulina supplement

Intervention Type DIETARY_SUPPLEMENT

Participants consume a 3g spirulina supplement 3 times daily for 5 consecutive days.

Eccentric exercise

Intervention Type PROCEDURE

On the morning of Day 3 (where Day 1 is when participants start taking supplements), participants perform a single bout of eccentric exercise. The exercise protocol is performed on a single leg and involves 300 (10 sets of 30 repetitions separated by 120 seconds) voluntary maximal, isokinetic, eccentric contractions of the knee extensor. Exercise is performed using a Biodex System 3 isokinetic dynamometer (Biodex Medical Systems, Shirley, NY, USA), and contractions are performed at 60◦/s over an 80◦ range of motion.

Placebo supplement

macronutrient matched placebo supplement three times daily for 5 days.

Group Type PLACEBO_COMPARATOR

Eccentric exercise

Intervention Type PROCEDURE

On the morning of Day 3 (where Day 1 is when participants start taking supplements), participants perform a single bout of eccentric exercise. The exercise protocol is performed on a single leg and involves 300 (10 sets of 30 repetitions separated by 120 seconds) voluntary maximal, isokinetic, eccentric contractions of the knee extensor. Exercise is performed using a Biodex System 3 isokinetic dynamometer (Biodex Medical Systems, Shirley, NY, USA), and contractions are performed at 60◦/s over an 80◦ range of motion.

Placebo supplement

Intervention Type DIETARY_SUPPLEMENT

Participants consume a macronutrient matched placebo supplement 3 times daily for 5 consecutive days.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Spirulina supplement

Participants consume a 3g spirulina supplement 3 times daily for 5 consecutive days.

Intervention Type DIETARY_SUPPLEMENT

Eccentric exercise

On the morning of Day 3 (where Day 1 is when participants start taking supplements), participants perform a single bout of eccentric exercise. The exercise protocol is performed on a single leg and involves 300 (10 sets of 30 repetitions separated by 120 seconds) voluntary maximal, isokinetic, eccentric contractions of the knee extensor. Exercise is performed using a Biodex System 3 isokinetic dynamometer (Biodex Medical Systems, Shirley, NY, USA), and contractions are performed at 60◦/s over an 80◦ range of motion.

Intervention Type PROCEDURE

Placebo supplement

Participants consume a macronutrient matched placebo supplement 3 times daily for 5 consecutive days.

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Are available and willing to attend St Luke's Campus, Exeter
* Age 18 - 40
* BMI 18.5 - 30 kg/m2
* The participant exercises / plays sport for \> 2 h/week, but doesn't do structured resistance strength training
* Self-reported as healthy (absence of injury or disease)
* Have no known food allergy to algae
* Are not taking any over the counter or prescribed medication that might interfere with study, e.g. anti-inflammatory medication
* Non-smoker

Exclusion Criteria

* Are unable to attend St Luke's Campus, Exeter
* Are out-with age range 18 - 40
* BMI below 18.5 or above 30 kg/m2
* The participant does not exercise
* The participant does regular structured resistance strength training
* Known injury or disease that might influence study outcomes
* Have a known food allergy to algae
* Are taking over the counter or prescribed medication that might interfere with study, e.g. anti-inflammatory medication
* Smoker
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

University of Exeter

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

University of Exeter

Exeter, , United Kingdom

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

United Kingdom

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Benjamin Wall, Prof

Role: CONTACT

+441392724774

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Ellen Williamson

Role: primary

07791054736

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

4530276

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.