The Effect of New Zealand Blackcurrant (NZBC) Supplementation on Recovery Following Strenuous Exercise

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

27 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-06-10

Study Completion Date

2018-09-01

Brief Summary

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The study aims to examine the effect of a New Zealand blackcurrant (NZBC) supplement on markers of muscle damage and recovery following strenuous resistance exercise. The investigation will compare responses between an experimental (NZBC capsule, 300 mg/day) and placebo (PLA capsule, 300 mg sugar) group. Participants will attend a screening session where they will consent to the study, complete a pre-activity medical questionnaire and have their height, weight and resting blood pressure measured. If the participants meet the inclusion criteria they will perform a familarisation session on the muscle strength assessment. Participants will be randomized to NZBC or placebo groups, and consume one capsule in the morning (between 6-10 am) for 12 days. This is a double-blinded study, which means that the participant and the study team will not know which group the participants are assigned to until the study is over. On day 8 participants will perform a strenuous bout of upper body resistance exercise on the isokinetic dynamometer (exercise device). Muscle strength and soreness, arm circumference, and elbow range of motion will be measured, and a fasted blood sample will be collected, before and 24, 48, 72 \& 96 hours after the muscle fatigue protocol (on days 9, 10, 11 \& 12). A marker of muscle damage (creatine kinase \[CK\] concentration) will be measured in the blood samples. Participants will also be asked to complete a 6-day dietary record, beginning on day 7 and ending on the final day of testing (day 12).

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Detailed Description

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Conditions

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Muscle Damage

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Randomised, parallel design.

Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Participants Investigators

Coded, capsules

Study Groups

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New Zealand blackcurrants (NZBC)

1 NZBC capsule (containing 300 mg active cassis containing 105 mg of anthocyanins, i.e. 35-50 % delphinidin-3-rutinoside, 5-20 % delphinidin-3-glucoside, 30-45 % cyanidin-3-rutinoside, 3-10 % cyanidin-3-glucoside), consumed in the morning, for 12 days.

Group Type EXPERIMENTAL

New Zealand blackcurrants (NZBC)

Intervention Type DIETARY_SUPPLEMENT

NZBC capsules containing anthocyanin-rich blackcurrant extract

Placebo (PLA)

1 placebo capsule (containing 300 mg microcrystalline cellulose M102), consumed in the morning, for 12 days.

Group Type PLACEBO_COMPARATOR

Placebo (PLA)

Intervention Type DIETARY_SUPPLEMENT

Placebo capsules containing microcrystalline cellulose

Interventions

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New Zealand blackcurrants (NZBC)

NZBC capsules containing anthocyanin-rich blackcurrant extract

Intervention Type DIETARY_SUPPLEMENT

Placebo (PLA)

Placebo capsules containing microcrystalline cellulose

Intervention Type DIETARY_SUPPLEMENT

Other Intervention Names

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NZBC extract supplement (Health Currancy Ltd [UK] / CurraNZ Ltd [NZ]) Placebo capsules

Eligibility Criteria

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Inclusion Criteria

* Males and Females
* 18 - 45 years old
* BMI: 19 - 29.9 kg/m2
* Healthy: no active disease process that could interfere with endpoints measured as determined by medical history

Exclusion Criteria

* Smoking and tobacco use
* Takes medication \[excluding contraception\]
* BMI ≥ 30 kg/m2
* Hypertensive (diastolic \> 90 and/or systolic blood pressure \> 140 mmHg)
* History of musculoskeletal upper limb injuries
* Performs regular resistance exercise (\> 2 sessions per week)
* Uses dietary supplements that could influence muscle recovery or function (e.g. protein supplements, antioxidants etc)

Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes