Neuromuscular Responses to Acute Beetroot Ingestion in Women Older Adults

NCT ID: NCT05337527

Last Updated: 2022-05-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

9 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-03-01

Study Completion Date

2022-04-10

Brief Summary

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Beetroot juice supplementation has shown the capacity for provoking different physiological effects (e.g. vasodilation and muscle contraction increments). However, the effects of beetroot juice ingestion on neuromuscular performance in women older adults are barely studied. In this randomized placebo-controlled study, we investigated the effects of beetroot acute supplementation in improving neuromuscular performance in women older adults

Detailed Description

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Beetroot juice supplementation has shown the capacity for provoking different physiological effects that could affect human performance (e.g. vasodilation and muscle contraction increments). Although this dietary supplement has been commonly used for improving sports performance in recreational or professional athletes, the scientific literature in older adults is scarce. Thus, in our knowledge, no previous studies have analyzed the side effects associated to ingestion in this population group. In this randomized placebo-controlled study, we investigated the effects of beetroot acute supplementation in improving neuromuscular performance and side effects associated with ingestion in women older adults.

Conditions

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Dietary Supplement Placebo

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Beetroot supplementation

One serving 70 mL of beetroot juice (6.4 mmol of NO3-; Beet-It-Pro Elite Shot, James White Drinks Ltd., Ipswich, UK) 3 h before initiating the testing session.

Group Type EXPERIMENTAL

beetroot juice

Intervention Type DIETARY_SUPPLEMENT

Acute effects of beetroot juice or placebo juice ingestion

Placebo supplementation

One serving 70 mL of beetroot juice placebo (0.04 mmol of NO3-; Beet-It-Pro Elite Shot, James White Drinks Ltd., Ipswich, UK) 3 h before initiating the testing session.

Group Type PLACEBO_COMPARATOR

beetroot juice

Intervention Type DIETARY_SUPPLEMENT

Acute effects of beetroot juice or placebo juice ingestion

Interventions

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beetroot juice

Acute effects of beetroot juice or placebo juice ingestion

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Women \>65 or \<85 years of age.
* In good health, as determined by the investigator's review of history.

Exclusion Criteria

Men and women \<65 or \>85 years of age Unable to provide informed consent Current smokers Significant orthopedic limitations or other contraindications to strenuous exercise Those taking proton pump inhibitors, antacids, xanthine oxidase inhibitors, or on hormone replacement therapy Those taking anti-coagulants or on anti-platelet therapy History of neuromuscular disease (e.g., cervical spondylotic radiculomyelpathy, lumbar spondylosis, amyotrophic lateral sclerosis, Guillain-Barré syndrome, and acquired demyelinating polyneuropathies) Cardiovascular disease (e.g., \> stage I hypertension, heart failure, myocardial infarction/ischemia significant myocardial or pericardial diseases (e.g. amyloidosis, constriction), Moderate or severe valvular disease, renal disease, liver disease, or anemia
Minimum Eligible Age

65 Years

Maximum Eligible Age

80 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Universidad Francisco de Vitoria

OTHER

Sponsor Role lead

Responsible Party

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Álvaro López Samanés

PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Alvaro López Samanes, PhD

Role: PRINCIPAL_INVESTIGATOR

Universidad Francisco de Vitoria

Locations

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Universidad Francisco de Vitoria

Pozuelo de Alarcón, Madrid, Spain

Site Status

Countries

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Spain

Other Identifiers

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uFrancisco_Vitoria_

Identifier Type: -

Identifier Source: org_study_id

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