Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
24 participants
INTERVENTIONAL
2010-11-30
Brief Summary
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Astaxanthin has been shown to be a powerfull anti-oxidant. Health benefits have been shown in animals and humans. Exercise enhancing effects have been shown in animals via enhancement of fat oxidation. We want to examine the effects of 4 weeks of astaxanthin supplementation on fat oxidation and cycling performance in trained cyclists
Objective of the study:
To test the hypothesis that 4 weeks supplementation with astaxanthin will improve fat oxidation and improve exercise performance in trained cyclists
Study design:
Double blind, placebo controlled study.
Study population:
Well trained cyclists between 18-30 years old
Intervention (if applicable):
astaxanthin (20 mg/day) or placebo for 4 weeks
Primary study parameters/outcome of the study:
performance on a time trial after 90 min steady state exercise.
Secundary study parameters/outcome of the study (if applicable):
substrate use plasma glucose plasma lactate plasma free fatty acid plasma astaxanthin
Nature and extent of the burden and risks associated with participation, benefit and group relatedness (if applicable):
The risks involved in participating in this experiment are minimal. Astaxanthin has been shown to be safe. Insertion of the catheters in a vein is comparable to a normal blood draw and the only risk is of a small local haematoma.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
BASIC_SCIENCE
DOUBLE
Study Groups
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astaxanthin
astaxanthin
astaxanthin
placebo
placebo
placebo
Interventions
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astaxanthin
astaxanthin
placebo
placebo
Eligibility Criteria
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Inclusion Criteria
* Male
* Age between 18 and 30 years
* Endurance trained (≥3 sessions of endurance exercise per week)
* VO2 max ≥ 50 ml/kg/min
* Training history of more than one year of ≥3 sessions of endurance exercise per week
* BMI \<25 kg/m2
Exclusion Criteria
* Smoking
18 Years
30 Years
MALE
Yes
Sponsors
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Maastricht University Medical Center
OTHER
Responsible Party
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MUMC
Locations
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Maastricht University
Maastricht, LI, Netherlands
Countries
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Central Contacts
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Facility Contacts
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References
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Klinkenberg LJ, Res PT, Haenen GR, Bast A, van Loon LJ, van Dieijen-Visser MP, Meex SJ. Effect of antioxidant supplementation on exercise-induced cardiac troponin release in cyclists: a randomized trial. PLoS One. 2013 Nov 19;8(11):e79280. doi: 10.1371/journal.pone.0079280. eCollection 2013.
Other Identifiers
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MEC 10-3-068
Identifier Type: -
Identifier Source: org_study_id
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