Examining The Effect of Blood Flow Restricted Aerobic Training on Mitochondrial Adaptations in Young Healthy Adults

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

19 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-05-06

Study Completion Date

2019-12-13

Brief Summary

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This parallel-arm trial study investigates the effects of restricting arterial blood flow during cycling exercise on citrate synthase. Participants will be randomized to either a blood flow restricted or non-blood flow restricted exercise training group. Both groups will complete seven, 30-minute exercise sessions over a 14-day period.

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Detailed Description

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Conditions

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Mitochondrial Biogenesis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

DOUBLE

Investigators Outcome Assessors

Allocation concealment, assessor blinding

Study Groups

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BFR

Group Type EXPERIMENTAL

BFR Exercise Training

Intervention Type OTHER

Participants will complete exercise training on a recumbent bike placed on a 45 degree incline (BFR).

CTL

Group Type EXPERIMENTAL

CTL Exercise Training

Intervention Type OTHER

Participants will complete exercise training on a recumbent bike placed on flat ground (CTL).

Interventions

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BFR Exercise Training

Participants will complete exercise training on a recumbent bike placed on a 45 degree incline (BFR).

Intervention Type OTHER

CTL Exercise Training

Participants will complete exercise training on a recumbent bike placed on flat ground (CTL).

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* 3 hours of physical activity per week
* No previous cycling training
* No concurrent involvement in another training program
* Body mass index \< 30 kg/m2