Examining the Impact of Blood Flow Restricted Aerobic Exercise on PGC-1α mRNA Expression in Young Healthy Males

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

13 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-10-01

Study Completion Date

2019-01-28

Brief Summary

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This crossover study investigates the effects of restricting arterial blood flow during cycling exercise on PGC-1α and its upstream signalling pathways. In a randomized order, participants will exercise once for 30 minutes with restricted blood flow and then will exercise once for 30 minutes with no blood flow restriction.

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Detailed Description

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Conditions

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Mitochondrial Biogenesis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

DOUBLE

Investigators Outcome Assessors

Allocation concealment, assessor blinding

Study Groups

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CTL - BFR

CTL Exercise then BFR Exercise

Group Type EXPERIMENTAL

BFR Exercise

Intervention Type OTHER

Participants will exercise on a recumbent bike placed on a 45 degree incline (BFR).

CTL Exercise

Intervention Type OTHER

Participants will exercise on a recumbent bike placed on flat ground (CTL).

BFR - CTL

BFR Exercise then CTL Exercise

Group Type EXPERIMENTAL

BFR Exercise

Intervention Type OTHER

Participants will exercise on a recumbent bike placed on a 45 degree incline (BFR).

CTL Exercise

Intervention Type OTHER

Participants will exercise on a recumbent bike placed on flat ground (CTL).

Interventions

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BFR Exercise

Participants will exercise on a recumbent bike placed on a 45 degree incline (BFR).

Intervention Type OTHER

CTL Exercise

Participants will exercise on a recumbent bike placed on flat ground (CTL).

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* 3 hours of physical activity per week
* No previous cycling training
* No concurrent involvement in another training program
* Body mass index \< 30 kg/m2