Bioenergetic Phenotypes and Cardiometabolic Health

NCT ID: NCT04427462

Last Updated: 2025-02-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

300 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-09-01

Study Completion Date

2026-06-30

Brief Summary

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This research study is about how daily activities, behaviors, and fitness affect the health and function of blood cells and their mitochondria, which are the powerhouses of the cells. These small mitochondria inside the cells make energy, and are very important for the health of the body.

Detailed Description

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Determine the impact of physical activity and obesity status on circulating cells mitochondrial function (e.g., fat vs. carbohydrates combustion capacity, total oxidative capacity, mitochondrial number and proton leak).

Conditions

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Healthy

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

Ages 8-10 years Boys and girls All ethnicity All BMI

Exclusion Criteria

severe persistent asthma exercise induced asthma autism spectrum disorder attention deficit hyperactivity disorder attention deficit disorder

* Opposition defiant disorder
* conduct disorder
* epilepsy
* chronic kidney disease
* hormonal disease
* autoimmune diseases
* bleeding disorders
* chronic infections
* mental health disorder
* Type 2 and Type 1 diabetes
* Other pre-existing medical conditions or medications as determined by the investigators to affect the outcomes of interest
Minimum Eligible Age

8 Years

Maximum Eligible Age

10 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Arkansas Children's Hospital Research Institute

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Elisabet Borsheim, Ph

Role: PRINCIPAL_INVESTIGATOR

Arkansas Children's Nutrition Center

Locations

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Arkansas Children's Nutrition Center

Little Rock, Arkansas, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Tonja C Nolen, MS

Role: CONTACT

501-364-3309

Audrey Martinez, MS, RD, LD

Role: CONTACT

501-364-3309

Facility Contacts

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Tonja Nolen, MS

Role: primary

501-364-2853

Other Identifiers

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260376

Identifier Type: -

Identifier Source: org_study_id

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