The Body's Response to Aerobic Versus Resistance Exercise

NCT ID: NCT00761163

Last Updated: 2013-01-17

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 25 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2007-02-28
• Study Completion Date: 2008-11-30

Brief Summary

The purpose of this study is to identify the body's response to aerobic vs. resistance exercise. Throughout this study, we will examine food intake, appetite, and physical and mental well-being before, during, and after aerobic and resistance exercise.

Conditions

Exercise

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: PREVENTION
• Blinding Strategy: NONE

Study Groups

1

Group Type: EXPERIMENTAL

Resistance Exercise

Intervention Type: OTHER

The subjects will complete 2 resistive exercise sessions on non-consecutive days that will be supervised by our laboratory staff. The following exercises will be performed using the Keiser Sports Health equipment in Ismail Health, Exercise, and Nutrition Center: seated row, double leg press, seated leg curl, chest press, and leg extension. The subjects will individually perform 3 sets of 8-10 repetitions at an exercise intensity of 70% of pre-determined maximal strength for these exercises. Each repetition will be performed in a slow (six to eight seconds) uniform fashion, giving equal time to the concentric (muscle shortening) and eccentric (muscle lengthening) portions. One minute of rest will be allowed between sets. The last repetition of the third set of each exercise will be done to voluntary fatigue or the performance of 12 repetitions.

2

Group Type: EXPERIMENTAL

Aerobic Exercise

Intervention Type: OTHER

The subjects will complete 2 aerobic exercise sessions on non-consecutive days that will also be supervised by our laboratory staff. The subjects will perform 45 minutes of aerobic exercise on a stationary bike at an exercise intensity of 70% of their heart-rate reserve.

3

Group Type: EXPERIMENTAL

Control (Non-exercise)

Intervention Type: OTHER

The subjects will also complete 2 non-exercise sessions on non-consecutive days that will also be supervised by our laboratory staff. These sessions will consist of incorporating diversionary tasks throughout a 45 minute period consisting of a variety of motor and psychological tasks (tests of hand steadiness, alertness, optical illusions, mental acuity, etc.)

Interventions

Resistance Exercise

The subjects will complete 2 resistive exercise sessions on non-consecutive days that will be supervised by our laboratory staff. The following exercises will be performed using the Keiser Sports Health equipment in Ismail Health, Exercise, and Nutrition Center: seated row, double leg press, seated leg curl, chest press, and leg extension. The subjects will individually perform 3 sets of 8-10 repetitions at an exercise intensity of 70% of pre-determined maximal strength for these exercises. Each repetition will be performed in a slow (six to eight seconds) uniform fashion, giving equal time to the concentric (muscle shortening) and eccentric (muscle lengthening) portions. One minute of rest will be allowed between sets. The last repetition of the third set of each exercise will be done to voluntary fatigue or the performance of 12 repetitions.

Intervention Type: OTHER

Aerobic Exercise

The subjects will complete 2 aerobic exercise sessions on non-consecutive days that will also be supervised by our laboratory staff. The subjects will perform 45 minutes of aerobic exercise on a stationary bike at an exercise intensity of 70% of their heart-rate reserve.

Intervention Type: OTHER

Control (Non-exercise)

The subjects will also complete 2 non-exercise sessions on non-consecutive days that will also be supervised by our laboratory staff. These sessions will consist of incorporating diversionary tasks throughout a 45 minute period consisting of a variety of motor and psychological tasks (tests of hand steadiness, alertness, optical illusions, mental acuity, etc.)

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Body mass index between 18-29 kg/m2
• Weight stable (< 4.5 kg weight change within last 6 months)
• Non-smoking
• Constant habitual activity patterns within last 3 months
• Non-diabetic
• Resistive exercise training (≥ 2 times a week) based on reported physical activity levels (questionnaire)
• Aerobic exercise training (≥ 2 times a week, 30-min sessions) based on reported physical activity levels (questionnaire)
• Confirmation of acceptability of eating the study test foods (macaroni casserole)
• Approved to participate in this study by our study physician and principle investigator

The older subjects must also meet the following eligibility criteria:

• Age range: 65 years and older
• Body fat (women: <38%; men: <28%)
• Normal resting EKG as assessed by a Cardiologist

The younger subjects must also meet the following eligibility criteria:

• Age range: 18-29 years
• Body fat (women: <28%; men: <18%)

Exclusion Criteria

• Body mass index: outside of the 18-29 kg/m2 range
• Gained or lost > 4.5 kg within the last 6 months
• Smoker (currently or within the last year)
• Intermittently been involved in a diet and/or exercise program within the last 3 months
• Clinically diagnosed as diabetic
• Did not perform resistive exercise training (currently or within the last 3 months) based on reported physical activity levels (questionnaire)
• Did not perform adequate aerobic exercise (currently or within the last 3 months) based on physical activity levels (questionnaire)
• Study food is found to be unacceptable for consumption by the subject
• Unapproved to participate in this study by our study physician and principle investigator

The older subjects:

• Age range: <65 yrs
• Body fat (women: >38%; men: >28%)
• Abnormal resting EKG (interpreted by a cardiologist) and assessed (for study exclusion) by our study physician, Arthur Rosen, MD

The younger subjects:

• Age range: outside the >29 yrs or <18 yrs
• Body fat (women: >28%; men: >18%)

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Purdue University

OTHER

Sponsor Role: lead

Responsible Party

Wayne Campbell

Wayne Campbell, Ph. D.

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Purdue University

West Lafayette, Indiana, United States

Countries

United States

References

Laan DJ, Leidy HJ, Lim E, Campbell WW. Effects and reproducibility of aerobic and resistance exercise on appetite and energy intake in young, physically active adults. Appl Physiol Nutr Metab. 2010 Dec;35(6):842-7. doi: 10.1139/H10-072.

Reference Type: DERIVED

PMID: 21164556 (View on PubMed)

Other Identifiers

NIH/NIA 5R01AG021911

Identifier Type: -

Identifier Source: secondary_id

0701004892

Identifier Type: -

Identifier Source: org_study_id