Independent and Combined Effects of Aerobic and Resistance Training on Blood Pressure

NCT ID: NCT03734146

Last Updated: 2018-11-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

69 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-07-15

Study Completion Date

2014-12-19

Brief Summary

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We compared the effects of 8 weeks of aerobic exercise only, resistance exercise only, or a combination of both on blood pressure in overweight or obese middle-aged adults with elevated blood pressure. Participants engaged in supervised exercise sessions 3 times per week for 60 minutes each session. Outcomes were assessed at baseline and after the 8-week intervention. Extra-intervention physical activity and diet were also assessed.

Detailed Description

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Conditions

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Cardiovascular Risk Factor

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

randomized controlled trial
Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

SINGLE

Outcome Assessors
The outcomes assessor was blinded to treatment group allocation.

Study Groups

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Aerobic exercise (AE)

Engage in supervised aerobic exercise for 60 minutes on 3 days per week for 8 weeks. Exercise is performed on a recumbent bike or treadmill at 50-80% of their heart rate reserve.

Group Type EXPERIMENTAL

Aerobic Exercise

Intervention Type BEHAVIORAL

180 minutes of moderate-vigorous intensity aerobic exercise per week

Resistance exercise (RE)

Engage in supervised resistance exercise for 60 minutes on 3 days per week for 8 weeks. Exercise consists of 3 sets of 8-12 repetitions of 12 exercises for the major muscle groups.

Group Type EXPERIMENTAL

Resistance Exercise

Intervention Type BEHAVIORAL

180 minutes of resistance exercise per week

Combined Resistance and Aerobic Exercise

Engage in supervised aerobic resistance exercise for 60 minutes on 3 days per week for 8 weeks. Exercise consists of 30 min aerobic exercise at 50-80% heart rate reserve and 30 min of resistance exercise comprising 2 sets of 8-12 repetitions of 9 exercises for the major muscle groups.

Group Type EXPERIMENTAL

Combined aerobic and resistance exercise

Intervention Type BEHAVIORAL

180 minutes of exercise per week with 90 minutes per week coming from moderate-vigorous intensity aerobic exercise and 90 minutes per week coming from resistance exercise

No training control

No exercise training. Participants will refrain from any moderate-vigorous exercise or resistance training for 8 weeks.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Aerobic Exercise

180 minutes of moderate-vigorous intensity aerobic exercise per week

Intervention Type BEHAVIORAL

Resistance Exercise

180 minutes of resistance exercise per week

Intervention Type BEHAVIORAL

Combined aerobic and resistance exercise

180 minutes of exercise per week with 90 minutes per week coming from moderate-vigorous intensity aerobic exercise and 90 minutes per week coming from resistance exercise

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Systolic/diastolic blood pressure of 120-159/80-99 mm Hg
* Non-smoking
* Overweight or obese, with a body mass index of 25-40 kg/m2
* Inactive--not meeting the aerobic or resistance physical activity guidelines, which means engaging in less than 150 minutes/wk of moderate intensity aerobic exercise and less than 2 days per week of resistance training over the past 3 months.

Exclusion Criteria

* Unstable coronary heart disease or decompensated heart failure
* Severe pulmonary hypertension or aortic stenosis
* Acute myocarditis, endocarditis, pericarditis, or aortic dissection
* Other medical condition that is life-threatening or that can interfere or be aggravated by the exercise training such as cancer, uncontrolled diabetes, severe pain or mobility limitations.
* Premenopausal women or postmenopausal women taking hormonal replacement therapy
* Pregnant women or anticipated pregnancy via IVF or other medical procedures during the course of the intervention
Minimum Eligible Age

45 Years

Maximum Eligible Age

74 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Iowa State University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Duck-chul Lee, PhD

Role: PRINCIPAL_INVESTIGATOR

Iowa State University

Other Identifiers

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14-330

Identifier Type: -

Identifier Source: org_study_id

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