Effects of Aerobic Exercise on Cognitive Function and Brain-derived Neurotrophic Factor in Young Adults

NCT ID: NCT02075944

Last Updated: 2014-06-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

130 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-02-28

Study Completion Date

2014-06-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The present study will investigate the effects of aerobic exercise on cognition and growth factors including brain-derived neurotrophic factor (BDNF) in young adults aged 15-21 years. The included subjects will be randomized to three different groups including one control group and two exercise groups. Subjects randomized to the exercise groups will complete 30 minutes of aerobic exercise 3 times a week for 9 weeks incorporating low (group I) or high (group II) intensity aerobic exercise. The exercise will be conducted as running or indoor cycling (supervised). At baseline and 9-weeks follow-up all subjects will complete two cognitive tests (measures of concentration and sustained attention), a maximal cycling test (direct measures of VO2max), an intelligence quotient test, anthropometric measures, fasting blood samples and blood samples immediately following the cycling test. The blood samples will be analyzed for growth factors including BDNF and metabolic factors.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Physical Conditioning, Human Cognition

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

FACTORIAL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

SINGLE

Investigators

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

High intensity aerobic exercise

30 minutes of high intensity aerobic exercise 3 times a weeks for 9 weeks - incorporation interval training

Group Type EXPERIMENTAL

High intensity aerobic exercise

Intervention Type BEHAVIORAL

Low intensity aerobic exercise

30 minutes of low intensity aerobic exercise 3 times a weeks for 9 weeks

Group Type EXPERIMENTAL

Low intensity aerobic exercise

Intervention Type BEHAVIORAL

Control

No intervention. Participants are told not to make any changes in their everyday life

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

High intensity aerobic exercise

Intervention Type BEHAVIORAL

Low intensity aerobic exercise

Intervention Type BEHAVIORAL

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* age 15-21

Exclusion Criteria

* injury preventing one from being physically active
Minimum Eligible Age

15 Years

Maximum Eligible Age

21 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

University of Southern Denmark

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Anna Bugge, Post Doc

PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Anne K Thorsen, Cand. Scient

Role: PRINCIPAL_INVESTIGATOR

University of Southern Denmark

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

University of Southern Denmark

Odense, , Denmark

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Denmark

References

Explore related publications, articles, or registry entries linked to this study.

Gejl AK, Bugge A, Ernst MT, Mortensen EL, Gejl KD, Andersen LB. Effects of 9 Weeks of High- or Moderate-Intensity Training on Cardiorespiratory Fitness, Inhibitory Control, and Plasma Brain-Derived Neurotrophic Factor in Danish Adolescents-A Randomized Controlled Trial. Scand J Med Sci Sports. 2024 Aug;34(8):e14703. doi: 10.1111/sms.14703.

Reference Type DERIVED
PMID: 39054765 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

S-20130171

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.