The Effect of Physical Activity on the Brain

NCT ID: NCT01475396

Last Updated: 2012-06-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE3

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-03-31

Study Completion Date

2012-12-31

Brief Summary

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Physical activity is thought to increase overall body functions and to decrease cardiovascular and stroke risk factors. Now the question arose, wether enhanced exercise could also exert positive influence on cognition in the aging brain. Therefore, 50 to 80 years old healthy subjects take part in a prospective study with regular sports activity during 6 months. Cognitive functions are detected with sensitive neuropsychological outcome measures, further investigations include MRT of the head, lactat- and other physical measures as well as detailed serum profiles. As a hypothesis, enhanced physical activity is suggested to predict better cognitive performance.

Detailed Description

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Conditions

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Aerobic Exercise Anaerobic Exercise Unchanged Condition

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Aerobic Exercise

Group Type EXPERIMENTAL

exercise

Intervention Type BEHAVIORAL

Anaerobic Exercise

Group Type EXPERIMENTAL

exercise

Intervention Type BEHAVIORAL

Unchanged condition

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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exercise

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* 50-80 years old
* healthy
* lesser activity

Exclusion Criteria

* regular physical activity
* diabetes
* stroke
* heavy smoking, drinking,
* BMI \< 20
* MMSE \< 25
Minimum Eligible Age

50 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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German Federal Ministry of Education and Research

OTHER_GOV

Sponsor Role collaborator

University Hospital Muenster

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Agnes Flooel, MD

Role: PRINCIPAL_INVESTIGATOR

University Hospital of Muenster

Stefan Knecht, MD

Role: STUDY_DIRECTOR

University Hospital of Muenster

Locations

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University Hospital of Muenster

Münster, North Rhine-Westphalia, Germany

Site Status

Countries

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Germany

Other Identifiers

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Exercise_Neuromod

Identifier Type: -

Identifier Source: org_study_id

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