MedDataX Logo

Aerobic Exercise to Improve Executive Language Function In Older Adults

NCT ID: NCT00979069

Last Updated: 2014-11-26

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

View full results

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-09-30

Study Completion Date

2012-01-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study is to see if exercise can improve brain function in older adults

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Recently, considerable attention has been devoted to examining the beneficial relationship between cognition and aerobic exercise in older adults. Specifically, the effects are thought to involve higher order cognitive processes, such as working memory, switching between tasks, and inhibiting irrelevant information, all of which are thought to be sub- served, in part, by the frontal lobes (Colcombe et al., 2006). Importantly, these areas also are most susceptible to age-related decline (Raz, 2000) and are essential resources for language production (Kemper \& Sumner, 2001; Murray \& Lenz, 2001). However, despite promising cognitive improvement, changes in frontally-mediated executive language functions have been widely ignored. This is unfortunate considering impaired word retrieval compromises communicative effectiveness, leading to frustration, depression, and withdrawal. Perhaps more importantly, communication ineffectiveness, particularly in the elderly, leads to difficulties interacting with health care professionals leading to further health care burdens. Since cognition, and specifically word retrieval difficulties, usually remain untreated, it is important to find treatment strategies for minimizing these deficits. Therefore, the short-term goal and the purpose of this proposal is to examine the potential of aerobic exercise to improve executive language function in older adults.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Aging

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Aerobic Group

12 weeks of aerobic exercise 3 times a week

Group Type EXPERIMENTAL

Aerobic group

Intervention Type BEHAVIORAL

12 weeks of aerobic exercise 3 times a week

Control Group

No contact control

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Aerobic group

12 weeks of aerobic exercise 3 times a week

Intervention Type BEHAVIORAL

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Consent of participants' primary health care physicians to participate in the aerobic exercise.
* Patients must not have participated in any consistent exercise program or experimental study for at least 3 months prior to enrollment.
* They must be capable of providing informed consent and complying with the trial procedures.

Exclusion Criteria

* Demented as defined by the Modified Mini Mental Status Exam.
* Unalterable travel schedules.
* Site accessibility constraints.
Minimum Eligible Age

65 Years

Maximum Eligible Age

89 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

US Department of Veterans Affairs

FED

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Joe R Nocera, PhD

Role: PRINCIPAL_INVESTIGATOR

Atlanta VA Medical and Rehab Center, Decatur, GA

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

North Florida/South Georgia Veterans Health System, Gainesville, FL

Gainesville, Florida, United States

Site Status

Atlanta VA Medical and Rehab Center, Decatur, GA

Decatur, Georgia, United States

Site Status

Countries

Review the countries where the study has at least one active or historical site.

United States

References

Explore related publications, articles, or registry entries linked to this study.

Nocera JR, McGregor KM, Hass CJ, Crosson B. Spin exercise improves semantic fluency in previously sedentary older adults. J Aging Phys Act. 2015 Jan;23(1):90-4. doi: 10.1123/japa.2013-0107. Epub 2014 Jan 14.

Reference Type RESULT
PMID: 24425525 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

E6860-M

Identifier Type: -

Identifier Source: org_study_id