Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
91 participants
OBSERVATIONAL
2020-12-09
2023-02-03
Brief Summary
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This study has 2 visits at the University of Kansas Medical Center Research in Exercise and Cardiovascular Health Laboratory. For the first visit, we will perform questionnaires about heart health, physical activity and overall health. Participants will then complete a submaximal exercise test on a seated stepper. Participants will also have a familiarization session to practice HIIT. The second visit will include cerebrovascular measures before, during, immediately after, and 30 minutes after performing HIIT.
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
CROSS_SECTIONAL
Study Groups
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Chronic Stroke
Individuals 40-80 years old who have had a stroke 6 months to 5 years ago.
Single, acute bout of high intensity interval exercise
Individuals will perform a single bout of high intensity interval exercise on a seated recumbent stepper. Participants will perform the pattern of high intensity interval exercise by switching between 1-minute high intensity stepping followed by 1-minute light, active recovery stepping for a total of 10 minutes.
CON
Control group (CON) comprised of age- and sex-matched healthy adults.
Single, acute bout of high intensity interval exercise
Individuals will perform a single bout of high intensity interval exercise on a seated recumbent stepper. Participants will perform the pattern of high intensity interval exercise by switching between 1-minute high intensity stepping followed by 1-minute light, active recovery stepping for a total of 10 minutes.
CONyoung
Healthy, young adult control group (CONyoung) who are age 18-30 years old.
Single, acute bout of high intensity interval exercise
Individuals will perform a single bout of high intensity interval exercise on a seated recumbent stepper. Participants will perform the pattern of high intensity interval exercise by switching between 1-minute high intensity stepping followed by 1-minute light, active recovery stepping for a total of 10 minutes.
Interventions
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Single, acute bout of high intensity interval exercise
Individuals will perform a single bout of high intensity interval exercise on a seated recumbent stepper. Participants will perform the pattern of high intensity interval exercise by switching between 1-minute high intensity stepping followed by 1-minute light, active recovery stepping for a total of 10 minutes.
Eligibility Criteria
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Inclusion Criteria
* Treated for stroke 6 months to 5 years ago
* Performs \<150 minutes of moderate intensity exercise per week
* Able to answer consenting questions and follow a 2-step command
* Matched age ± 5 years to participant with chronic stroke
* Matched sex to participant with chronic stroke
* Performs \<150 minutes of moderate intensity exercise per week
* Able to answer consenting questions and follow a 2-step command
* Age 18-30 years old
* Low cardiac risk (defined by the American College of Sports Medicine)
* Able to find TCD signal on the right or left MCA
Exclusion Criteria
* Symptoms of COVID-19 and/or Positive COVID-19 test within the past 3 months
* Unable to stand from a sitting position without physical assistance
* Recent joint replacement/surgery/poor motor control that limits ability to perform exercise on a recumbent stepper
* Insulin injection dependent diabetes
* Dependent on supplementary oxygen
* History of other neurological disease (Multiple Sclerosis, Alzheimer's disease, Parkinson's disease)
* Unable to find TCD signal on the stroke-affected or non-affected MCA.
* Symptoms of COVID-19 and/or Positive COVID-19 test within the past 3 months
* Unable to stand from a sitting position without physical assistance
* Recent joint replacement/surgery/poor motor control that limits ability to perform exercise on a recumbent stepper
* Insulin injection dependent diabetes
* Dependent on supplementary oxygen
* History of other neurological disease (Multiple Sclerosis, Alzheimer's disease, Parkinson's disease)
* Unable to find TCD signal on the right or left MCA.
18 Years
80 Years
ALL
Yes
Sponsors
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University of Kansas Medical Center
OTHER
Responsible Party
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Principal Investigators
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Sandra A Billinger, PhD
Role: PRINCIPAL_INVESTIGATOR
University of Kansas Medical Center
Locations
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University of Kansas Medical Center
Kansas City, Kansas, United States
Countries
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Other Identifiers
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STUDY00146161
Identifier Type: -
Identifier Source: org_study_id
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