High Intensity Interval Training in Chronic Stroke

NCT ID: NCT06474832

Last Updated: 2024-09-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

32 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-07-16

Study Completion Date

2025-12-31

Brief Summary

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Both gait and cardiovascular dysfunction are primary factors limiting community ambulation for stroke individuals. Increased gait variability and asymmetry contributes to a higher risk of falls, leading to reduced physical activity, decreased cardiorespiratory endurance, and increased walking economy and sympathetic nervous system activity, thereby potentially triggering secondary strokes. Previous studies have primarily focused on the significant improvements in walking endurance and speed with high-intensity interval training (HIIT) on a treadmill, leaving a gap in understanding the effects of HIIT on oxygen uptake efficiency slope (OUES) and gait quality for stroke individuals using a stationary bicycle ergometer with exergaming. Therefore, this study aims to investigate the effects of HIIT using a stationary bicycle ergometer on improving cardiorespiratory fitness and gait quality in individuals with chronic stroke.

Detailed Description

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Conditions

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Chronic Stroke

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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High-intensity interval training group

The intervention is a 42-minute session and 3-sessions/week, totaling 8 weeks.

Group Type EXPERIMENTAL

High-intensity interval training

Intervention Type OTHER

Training on a stationary bike and integrated with exergame (Jbike, JACFIT, USA), the exercise games connect to a map in the app through sensors, allowing players from different countries to ride together and complete the map, thus increasing the diversity of the training, including a warm-up and cool-down at 30% HRR for 5 minutes each. Perform HIIT with 5 intervals at 80% heart rate reserve (HRR), each interval lasting 4 minutes, with 3-minute intervals at 40% HRR between each interval.

Moderate intensity continuous training group

The intervention is a 45-minute session and 3-sessions/week, totaling 8 weeks.

Group Type ACTIVE_COMPARATOR

Moderate intensity continuous training

Intervention Type OTHER

Training on a stationary bike and integrated with exergame (Jbike, JACFIT, USA), the exercise games connect to a map in the app through sensors, allowing players from different countries to ride together and complete the map, thus increasing the diversity of the training, including a warm-up and cool-down at 30% HRR for 5 minutes each. Perform continuous exercise at 59% HRR for 35 minutes.

Interventions

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High-intensity interval training

Training on a stationary bike and integrated with exergame (Jbike, JACFIT, USA), the exercise games connect to a map in the app through sensors, allowing players from different countries to ride together and complete the map, thus increasing the diversity of the training, including a warm-up and cool-down at 30% HRR for 5 minutes each. Perform HIIT with 5 intervals at 80% heart rate reserve (HRR), each interval lasting 4 minutes, with 3-minute intervals at 40% HRR between each interval.

Intervention Type OTHER

Moderate intensity continuous training

Training on a stationary bike and integrated with exergame (Jbike, JACFIT, USA), the exercise games connect to a map in the app through sensors, allowing players from different countries to ride together and complete the map, thus increasing the diversity of the training, including a warm-up and cool-down at 30% HRR for 5 minutes each. Perform continuous exercise at 59% HRR for 35 minutes.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Aged 18-69 years
* At least 6 months post-stroke
* Functional Ambulation Category (FAC) ≥ 3
* Mini-Mental State Examination (MMSE) ≥ 24
* Able to walk 10 meters overground with or without assistive devices

Exclusion Criteria

* Unstable cardiopulmonary conditions within the last 3 months
* Other chronic neurological disorders
* Contraindications to exercise as recommended by the American College of Sports Medicine (ACSM)
* Severe lower limb spasticity (Modified Ashworth Scale \> 2 points)
* Implanted pacemaker or cardioverter defibrillator
Minimum Eligible Age

18 Years

Maximum Eligible Age

69 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Yang Ming Chiao Tung University

OTHER

Sponsor Role lead

Responsible Party

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Yea-Ru Yang

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Department of Physical Therapy and Assistive Technology, National Yang Ming Chiao Tung University

Taipei, , Taiwan

Site Status RECRUITING

Countries

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Taiwan

Central Contacts

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Yea-Ru Yang, PhD

Role: CONTACT

+886-2-2826-7279

Facility Contacts

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Yea-Ru Yang, PhD

Role: primary

+886-2-2826-7279

Other Identifiers

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NYCU113060AF

Identifier Type: -

Identifier Source: org_study_id

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