Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
172 participants
OBSERVATIONAL
2004-11-30
2009-08-31
Brief Summary
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Detailed Description
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Participants complete 4 visits over several months. The first visit entails a clinical evaluation and memory testing involving the use of paper and pencil testing. The second visit is an MRI brain scan which lasts approximately one hour. The third visit involves drawing blood for laboratory testing and blood banking for future lab studies, lasting roughly 4 hours. The glucose tolerance test is administered. The fourth and final visit is an assessment of the participant's metabolism and exercise testing. This visit lasts approximately two hours.
Conditions
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Study Design
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CASE_CONTROL
PROSPECTIVE
Study Groups
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1
elderly people who have normal cognition
No interventions assigned to this group
2
elderly people who have mild to moderate Alzheimer's disease
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* Healthy male or female
* Normal control volunteers and early Alzheimer's disease patients
* Clinical Dementia Rating of 0, 0.5, or 1.0
* On stable doses of medications
Exclusion Criteria
* Schizophrenia
* Clinical signs of depression; major depression; mental health disorder; nervous system disorder
* Significant visual/auditory impairment
* Significant system illness; cancer
* Pacemaker/metal
* Thyroid problems
* Kidney dialysis
* Organ transplant
* Alcoholism
* Heart surgery
* Insulin
65 Years
ALL
Yes
Sponsors
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University of Kansas
OTHER
National Institute on Aging (NIA)
NIH
University of Kansas Medical Center
OTHER
Responsible Party
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Principal Investigators
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Jeffrey Burns, MD
Role: PRINCIPAL_INVESTIGATOR
University of Kansas Medical Center, Landon Center on Aging
Locations
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University of Kansas Medical Center
Kansas City, Kansas, United States
Countries
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Other Identifiers
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IA0089
Identifier Type: -
Identifier Source: org_study_id
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