Two Time a Week vs. Five Time a Week Blood Flow Restriction Training Program for the Lower Extremity.

NCT ID: NCT05342909

Last Updated: 2022-04-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

55 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-09-01

Study Completion Date

2022-06-30

Brief Summary

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This study will randomize healthy adults who regularly perform resistance training exercises for the lower extremities (2x a week) to one of three groups: a blood flow restriction (BFR) exercise group that trains 2x a week, a BFR exercise group that trains 5x a week, and a control group that does not perform any additional BFR exercise. Those randomized to the BFR groups will perform the unilateral 90-0 knee extension exercise followed by the bilateral squat. Subjects will have the BFR applied to their dominant lower extremity and will perform 4 sets (30/15/15/15 reps) per exercise. Training will initial start at 30% of 1RM with training intensity increased by 5% every 2 weeks. The training program will last 8 weeks.

Pre- and posttests include ultrasound imaging of the dominant leg rectus femoris and strength testing via hand held dynamometry.

Detailed Description

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Conditions

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Blood Flow Restriction Training

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors
The outcomes assessors are blinded to group allocation.

Study Groups

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5x a week BFR training group

Subjects will perform 2 exercises (LAQ and squat) with BFR applied to dominant thigh daily (5x/wk). Exercises performed for 4 sets (30/15/15/15 reps) initially at 30% 1RM; with load increased by 5% every 2 weeks. Training program lasts for 8 weeks. They are also to continue with their regular independent exercise program.

Group Type EXPERIMENTAL

5x a week BFR training group

Intervention Type OTHER

This group will perform the two exercises 5x a week with blood flow restriction, set to 80% of limb occlusion pressure, applied to the dominant thigh.

2x a week BFR training group

Subjects will perform 2 exercises (LAQ and squat) with BFR applied to dominant thigh twice a week (2x/wk). Exercises performed for 4 sets (30/15/15/15 reps) initially at 30% 1RM; with load increased by 5% every 2 weeks. Training program lasts for 8 weeks. They are also to continue with their regular independent exercise program.

Group Type EXPERIMENTAL

2x a week BFR training group

Intervention Type OTHER

This group will perform the two exercises 2x a week with blood flow restriction, set to 80% of limb occlusion pressure, applied to the dominant thigh.

Control group

This group will not perform any BFR exercises. They are to continue with their regular independent exercise program.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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5x a week BFR training group

This group will perform the two exercises 5x a week with blood flow restriction, set to 80% of limb occlusion pressure, applied to the dominant thigh.

Intervention Type OTHER

2x a week BFR training group

This group will perform the two exercises 2x a week with blood flow restriction, set to 80% of limb occlusion pressure, applied to the dominant thigh.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

\-

Exclusion Criteria

\-
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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George Fox University

OTHER

Sponsor Role lead

Responsible Party

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Jason Brumitt

Associate Professor of Physical Therapy

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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JASON BRUMITT, PhD

Role: PRINCIPAL_INVESTIGATOR

College of Physical Therapy; George Fox University

Locations

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George Fox University School of Physical Therapy

Newberg, Oregon, United States

Site Status RECRUITING

George Fox University

Newberg, Oregon, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Jason Brumitt, PhD

Role: CONTACT

5035542461

Facility Contacts

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Jason Brumitt, PhD

Role: primary

503-554-2461

Jason Brumitt, PhD

Role: backup

5035542461

JASON BRUMITT, PhD

Role: primary

503-554-2461

Other Identifiers

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GeorgeFoxU

Identifier Type: -

Identifier Source: org_study_id

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