Frequency of Aerobic/Resistance Training in Older Women

NCT ID: NCT01031394

Last Updated: 2015-10-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

105 participants

Study Classification

INTERVENTIONAL

Study Start Date

2004-01-31

Study Completion Date

2011-03-31

Brief Summary

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The objective of this study is to provide insight into the effects combined training frequency has on improving fitness, ease of physical activity, and maintenance of a high total energy expenditure. Such information is critical to our understanding of ways to improve well-being, quality of life, and independence of an aging population. 105 participants will be enrolled in this study. The length of time for your involvement in the study will be 32 weeks. You will undergo the procedures listed in this consent form on 3 separate occasions-initially at your entry, at 16 weeks and again at 32 weeks.

Detailed Description

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Frequency of aerobic/resistance training in older women

Abstract Combined aerobic and resistance training have unique benefits for maintaining a physical activity (PA). However, the optimal training program for combining these two modes of training in older adults is unknown. This study builds on current and past studies showing that training induced gains in aerobic fitness, muscle strength, and ease of PA are important for maintaining an active lifestyle, a favorable body composition, and high bone density. Traditionally 3 d/wk combined training has been felt to be optimal while recent studies suggest 1 d/wk combined training may create similar adaptations as more frequent training. However, our previous and ongoing studies suggest that 1 d/wk combined aerobic and resistance training (C1) may be insufficient stimulus to induce optimal adaptations and that 3 d/wk combined training (C3) may be too frequent a stimulus for older adults. This study will enable us to compare the effects of C1, 2 d/wk combined training (C2), and C3 on fitness, body composition, ease of PA, PA, and total free-living energy expenditure (TEE). We hypothesize that C2 will result in a larger increase in muscle size, bone density, strength, aerobic capacity, power, ease of PA, PA, and TEE than either C1 or C3. Circulating cytokines and psychological mood states linked to chronic overstress will also be examined. Objectives: We will examine changes in circulating cytokines, mood states, muscle size, bone density, aerobic capacity, strength, power, ease of PA, PA, and TEE following 16 and 32 wks training. Design: We will to evaluate 78 (\>60 yrs) Black and White women matched for age, race, and BMI into C1, C2, or C3 groups prior to, after 16, and after 32 wks training. Women will undergo evaluation of metabolic parameters in a General Clinical Research Center. Significance: This study should provide insight into the effects combined training frequency has on improving fitness, ease of PA, and maintenance of a high TEE. Such information is critical to our understanding of ways to improve well being, quality of life, and independence of an aging population.

Conditions

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Aging

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Group 1

1 aerobic and 1 resistance training per week

Group Type ACTIVE_COMPARATOR

Frequency of Aerobic/Resistance Training - 3 to 3

Intervention Type OTHER

comparing group results based upon frequency of exercise

Group 2

2 aerobic and 2 resistance training each per week

Group Type ACTIVE_COMPARATOR

Frequency of Aerobic/Resistance Training - 3 to 3

Intervention Type OTHER

comparing group results based upon frequency of exercise

Group 3

3 aerobic and 3 resistance training per week

Group Type ACTIVE_COMPARATOR

Frequency of Aerobic/Resistance Training - 3 to 3

Intervention Type OTHER

comparing group results based upon frequency of exercise

Interventions

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Frequency of Aerobic/Resistance Training - 3 to 3

comparing group results based upon frequency of exercise

Intervention Type OTHER

Other Intervention Names

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freqency of aerobic and resistance training

Eligibility Criteria

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Inclusion Criteria

* healthy women over 60 years of age,
* Caucasian or African-American.

Exclusion Criteria

* smoking,
* diabetes,
* osteoporosis,
* inability to coperform weight bearing exercises, currently performing to much exercise.
Minimum Eligible Age

60 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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National Institute on Aging (NIA)

NIH

Sponsor Role collaborator

University of Alabama at Birmingham

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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UAB

Birmingham, Alabama, United States

Site Status

Countries

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United States

References

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Martins C, Gower B, Hunter GR. Metabolic adaptation after combined resistance and aerobic exercise training in older women. Obesity (Silver Spring). 2022 Jul;30(7):1453-1461. doi: 10.1002/oby.23450. Epub 2022 Jun 21.

Reference Type DERIVED
PMID: 35729736 (View on PubMed)

Carter SJ, Baranauskas MN, Singh H, Martins C, Hunter GR. ARTE index revisited: linking biomarkers of cardiometabolic health with free-living physical activity in postmenopausal women. Am J Physiol Regul Integr Comp Physiol. 2022 Apr 1;322(4):R292-R298. doi: 10.1152/ajpregu.00075.2021. Epub 2022 Jan 26.

Reference Type DERIVED
PMID: 35081314 (View on PubMed)

Other Identifiers

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R01AG027084

Identifier Type: NIH

Identifier Source: secondary_id

View Link

F050820002

Identifier Type: -

Identifier Source: org_study_id

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