Study Results
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View full resultsBasic Information
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COMPLETED
NA
20 participants
INTERVENTIONAL
2019-11-22
2023-05-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
BASIC_SCIENCE
NONE
Study Groups
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Older Men
Control Period
Participants completed an 8-week control period of normal lifestyle.
Exercise Period
Participants completed an 8-week exercise intervention period of remotely supervised home-based non-weight-bearing all-extremity high intensity interval training (NWA-HIIT). NWA-HIIT consisted of 4x4-min bouts at 90% of maximal heart rate (HRmax) interspersed by 3x3-min bouts at 70% of HRmax. A 10-min warm-up and 5-minute cool-down at 70% of HRmax were included.
Older Postmenopausal Women
Control Period
Participants completed an 8-week control period of normal lifestyle.
Exercise Period
Participants completed an 8-week exercise intervention period of remotely supervised home-based non-weight-bearing all-extremity high intensity interval training (NWA-HIIT). NWA-HIIT consisted of 4x4-min bouts at 90% of maximal heart rate (HRmax) interspersed by 3x3-min bouts at 70% of HRmax. A 10-min warm-up and 5-minute cool-down at 70% of HRmax were included.
Interventions
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Control Period
Participants completed an 8-week control period of normal lifestyle.
Exercise Period
Participants completed an 8-week exercise intervention period of remotely supervised home-based non-weight-bearing all-extremity high intensity interval training (NWA-HIIT). NWA-HIIT consisted of 4x4-min bouts at 90% of maximal heart rate (HRmax) interspersed by 3x3-min bouts at 70% of HRmax. A 10-min warm-up and 5-minute cool-down at 70% of HRmax were included.
Eligibility Criteria
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Inclusion Criteria
* men and women
* women must be postmenopausal (either natural or surgical)
* 60 to 79 years of age
Exclusion Criteria
* myocardial ischemia during maximal graded exercise test
* major chronic clinical disease (e.g., diabetes, renal or hepatic disease or infection with hepatitis B, C, or HIV)
* seizures, or other relevant on-going or recurrent illness
* recent (within 3 months) or recurrent hospitalizations
* systolic blood pressure \< 100 mmHg
* body mass index \> 35 kg/m\^2
* \>5% weight change in past 3 months or unwilling to remain weight stable during study participation
* use of tobacco products including smoking traditional or e-cigarettes
* use of hormone replacement therapy in women or men (e.g., estrogen, progesterone or testosterone)
* regular aerobic exercise training (≥30 min/session and ≥ 3 days/week)
60 Years
79 Years
ALL
Yes
Sponsors
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National Institute on Aging (NIA)
NIH
University of Florida
OTHER
Responsible Party
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Principal Investigators
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Demetra Christou, PhD
Role: PRINCIPAL_INVESTIGATOR
University of Florida
Locations
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Integrative Cardiovasculal Physiology Laboratory, University of Florida
Gainesville, Florida, United States
Countries
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Provided Documents
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Document Type: Study Protocol and Statistical Analysis Plan
Document Type: Informed Consent Form
Other Identifiers
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IRB201902165- N
Identifier Type: -
Identifier Source: org_study_id
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