Effects of Training Intensity on the CHD Risk Factors in Postmenopausal Women

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Study Classification

INTERVENTIONAL

Brief Summary

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The purpose of this research is to find out whether training at different exercise intensities reduces the risk of developing cardiovascular disease (CVD) to a different extent. Heart attacks and stroke are the leading cause of death in older women. Reduced variability of the heart rate and increased dips and swings in blood pressure are risks factors that predict the chance of developing CVD as are increased levels of clotting protein fibrinogen and plasminogen activator inhibitor 1, and high levels of LDL-cholesterol (\>160mg/dl). We will be measuring all of these risk factors and any changes in your body fat level before you start training and after 15 and 30 weeks of training in the form of walking. At the present time the effects of exercise intensity on these factors are not well understood. This study will add to the basic understanding of these issues and allow us to recommend to postmenopausal women optimal exercise intensities to lose body fat and reduce the risk of developing CVD.

Detailed Description

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Conditions

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Cardiovascular Diseases Coronary Disease

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Interventions

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Exercise

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Postmenopausal and preferably on hormone replacement therapy
* In good general health
* Have a body mass index (BMI, weight in kg/height in m2) of between 25 and 40
* Exercise less than 20 min/day two days a week

Minimum Eligible Age

50 Years

Maximum Eligible Age

65 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Locations

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3060G Central Campus Recreation Bldg 401 Washtenaw Ave.

Ann Arbor, Michigan, United States

Site Status

Countries

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United States

Other Identifiers

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NCRR-M01RR00042-1647

Identifier Type: -

Identifier Source: org_study_id

M01RR000042

Identifier Type: NIH

Identifier Source: secondary_id

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