Physiological Outcomes of High-intensity Interval Training With Post-exercise Blood Flow Restriction

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-07-01

Study Completion Date

2024-09-30

Brief Summary

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This research study revolves around the physiological outcomes of using post-exercise blood flow restriction (BFR) with high intensity short interval training (ST) The main aims of this study are to compare (i) aerobic performance outcomes, and (ii) anaerobic and muscular performance outcomes - between 2 groups of participants after either undergoing 3 weeks of ST + post-exercise BFR (BFR-ST) or traditional ST.

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Detailed Description

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This research study revolves around the physiological outcomes of using post-exercise blood flow restriction (BFR) with high-intensity interval exercise training (HIIT), specifically high intensity short interval training (ST) protocol of 30s work, 30s rest, for the recreational endurance athlete. In previous research, it has been shown that using BFR during rest intervals of a ST protocol would elicit greater physiological stresses in terms of higher heart rate, greater muscle activation, reduced oxygenation within the muscle tissue during exercise, and increased blood lactate post-exercise as compared with the control condition. However, the physiological outcomes of this type of training method over a longer-term (9 sessions over 3 weeks) have not been explored. The main aims of this study is to compare the physiological outcomes, - (i) aerobic performance outcomes, and (ii) anaerobic and muscular performance outcomes - between 2 groups of participants after either undergoing 3 weeks of ST + post-exercise BFR (BFR-ST) or traditional ST . The hypotheses for this study are: the BFR-ST group would experience a (i) greater improvement in maximal aerobic capacity, function and time trial performance and, (ii) greater improvement in anaerobic power and capacity as well as muscular strength and power, as compared with the ST group.

Conditions

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Exercise Performance

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Two groups exposed to 9 sessions of high intensity short interval training with or without blood flow restriction between sets of exercise.

Primary Study Purpose

OTHER

Blinding Strategy

SINGLE

Participants

Sham treatment of altitude exposure in an environmental chamber.

Study Groups

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Blood flow restriction with short interval training (BFR-ST)

9 sessions of high intensity short interval training with blood flow restriction.

Group Type EXPERIMENTAL

BFR-ST

Intervention Type OTHER

Undergo 9 sessions of high intensity short interval training involving 3 sets of 8-10 repetitions of 30 secs interval cycling and 30 secs recovery at 100-110% of maximal aerobic power. In between sets there will be 3 mins of passive rest. Blood flow restriction will be applied for 2 mins during the passive rest at 80% of limb occlusion pressure.

Sham altitude with short interval training (ST)

9 sessions of high intensity short interval training in an altitude chamber.

Group Type SHAM_COMPARATOR

ST

Intervention Type OTHER

Undergo 9 sessions of high intensity short interval training involving 3 sets of 8-10 repetitions of 30 secs interval cycling and 30 secs recovery at 100-110% of maximal aerobic power. In between sets there will be 3 mins of passive rest. Cycling will be conducted in an environmental chamber and participants informed that the altitude is set to 2500m - actual altitude will be sea level.

Interventions

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BFR-ST

Undergo 9 sessions of high intensity short interval training involving 3 sets of 8-10 repetitions of 30 secs interval cycling and 30 secs recovery at 100-110% of maximal aerobic power. In between sets there will be 3 mins of passive rest. Blood flow restriction will be applied for 2 mins during the passive rest at 80% of limb occlusion pressure.

Intervention Type OTHER

ST

Undergo 9 sessions of high intensity short interval training involving 3 sets of 8-10 repetitions of 30 secs interval cycling and 30 secs recovery at 100-110% of maximal aerobic power. In between sets there will be 3 mins of passive rest. Cycling will be conducted in an environmental chamber and participants informed that the altitude is set to 2500m - actual altitude will be sea level.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Male
* 18-40 years
* Actively performing endurance exercise (running or cycling) for at least 2 sessions (1 - 1.5h) per week
* Healthy (free from illnesses) and no musculoskeletal injuries for the past 6 months
* No history of cardiometabolic, vascular diseases or similar conditions (e.g., high blood pressure, peripheral vascular diseases, heart diseases, metabolic syndrome, diabetes, stroke, etc.).
* Pass the pre-participation health screening tests - Physical Activity Readiness Questionnaire for Everyone (PAR-Q+) and Australian Institute of Sport Blood Flow Restriction (AIS BFR) pre-screening questionnaire (no history of any risk factors).
* Achieve a maximum oxygen uptake (VO2max) of ≥40ml/kg/min during a maximal aerobic power cycling screening test.
* Non-smoker
* Drink alcohol less than 3 times each week and less than 3 drinks each time

* History of asthma or taking medication for asthma.

Exclusion Criteria

* Persons with any form of illnesses and/or musculoskeletal injuries for the past 6 months
* Any history of cardiometabolic, vascular diseases or similar conditions which may worsen with the use of blood flow restriction during exercise
* Fail the pre-participation health screening tests
* Below 40ml/kg/min VO2max during maximal aerobic power cycling test
* Smoker

Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes