The Efficacy of REHACOP Program in Schizophrenia

NCT ID: NCT02796417

Last Updated: 2016-06-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

111 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-03-31

Study Completion Date

2014-04-30

Brief Summary

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This study examined the efficacy of an integrative cognitive remediation program (REHACOP) to improve cognition, social cognition, clinical symptoms and functional outcome in patients with schizophrenia.

Detailed Description

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Conditions

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Schizophrenia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Rehacop group

Cognitive rehabilitation

Group Type EXPERIMENTAL

REHACOP

Intervention Type BEHAVIORAL

REHACOP group consists of 90-minute-long sessions 3 days per week. Specifically, REHACOP group remediation consisted of: Attention unit (4 weeks) training sustained, selective, alternant and divided attention; Memory unit (3 weeks) focusing on visual and verbal learning, recall and recognizing memory; Language unit (3 weeks) including grammar, syntax, vocabulary, verbal fluency, verbal comprehension, abstract language; Executive functions unit (2 weeks) training cognitive planning, proverbs, analogies; and Social cognition unit (1 week) exercising theory of mind, social reasoning and moral dilemmas

Control group

Occupational activities

Group Type ACTIVE_COMPARATOR

Occupational activities

Intervention Type BEHAVIORAL

Occupational group activities conducted included drawing, gardening, reading the daily news and constructing using different materials (such as paper or wood).

Interventions

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REHACOP

REHACOP group consists of 90-minute-long sessions 3 days per week. Specifically, REHACOP group remediation consisted of: Attention unit (4 weeks) training sustained, selective, alternant and divided attention; Memory unit (3 weeks) focusing on visual and verbal learning, recall and recognizing memory; Language unit (3 weeks) including grammar, syntax, vocabulary, verbal fluency, verbal comprehension, abstract language; Executive functions unit (2 weeks) training cognitive planning, proverbs, analogies; and Social cognition unit (1 week) exercising theory of mind, social reasoning and moral dilemmas

Intervention Type BEHAVIORAL

Occupational activities

Occupational group activities conducted included drawing, gardening, reading the daily news and constructing using different materials (such as paper or wood).

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* diagnostic criteria for Schizophrenia according to American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR)

Exclusion Criteria

* evidence of alcohol or drug abuse in the last 30 days
* previous history of significant lack of consciousness
* mental retardation
* relevant neurological or medical condition
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Deusto

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Natalia Ojeda, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Deusto

Locations

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University of Deusto

Bilbao, Biskai, Spain

Site Status

Countries

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Spain

References

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Pena J, Ibarretxe-Bilbao N, Sanchez P, Uriarte JJ, Elizagarate E, Gutierrez M, Ojeda N. Mechanisms of functional improvement through cognitive rehabilitation in schizophrenia. J Psychiatr Res. 2018 Jun;101:21-27. doi: 10.1016/j.jpsychires.2018.03.002. Epub 2018 Mar 6.

Reference Type DERIVED
PMID: 29525739 (View on PubMed)

Pena J, Ibarretxe-Bilbao N, Sanchez P, Iriarte MB, Elizagarate E, Garay MA, Gutierrez M, Iribarren A, Ojeda N. Combining social cognitive treatment, cognitive remediation, and functional skills training in schizophrenia: a randomized controlled trial. NPJ Schizophr. 2016 Nov 9;2:16037. doi: 10.1038/npjschz.2016.37. eCollection 2016.

Reference Type DERIVED
PMID: 27868083 (View on PubMed)

Other Identifiers

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NSMC-003-UD

Identifier Type: -

Identifier Source: org_study_id

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